|Description||GRA Ex-25 is an orally active human glucagon receptor antagonist in a transgenic murine pharmacodynamic model, with IC50 of 56 and 55 nM for rat and human glucagon receptors, respectively. GCGR has evolved as an attractive therapeutic target for the treatment of type II diabetes mellitus.|
|Synonyms||3-(4-((1-(4-(tert-butyl)cyclohexyl)-3-(4-(trifluoromethoxy)phenyl)ureido)methyl)benzamido)propanoic acid; GRA Ex-25; GRA Ex 25; GRA Ex25; GRAEx-25; GRAEx 25; GRAEx25.|
|Storage||Store in a cool and dry place (or refer to the Certificate of Analysis).|
|Boiling Point||726.3±60.0 °C at 760 Torr|
|Melting Point||152-154 °C|
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