Gomisin G - CAS 62956-48-3
Catalog number:
62956-48-3
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C30H32O9
Molecular Weight:
536.6
COA:
Inquire
Targets:
HIV
Description:
Gomisin G, carboxylic acid with additional oxygen functions, exhibited the most potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 microgram/mL and 300, respectively.
Publictions citing BOC Sciences Products
  • >> More
Purity:
≥98%
Appearance:
Solid Powder
Synonyms:
Benzo(3,4)cycloocta(1,2-f)(1,3)benzodioxole-7,8-diol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, 8-benzoate, (6S,7S,8S,13aS)-;
Solubility:
Soluble in DMSO
Storage:
Store at -20 °C
MSDS:
Inquire
Application:
anti-HIV
Quality Standard:
Enterprise Standard
Shelf Life:
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Quantity:
Milligrams-Grams
InChIKey:
OFDWKHIQKPKRKY-DSASHONVSA-N
InChI:
1S/C30H32O9/c1-16-12-18-13-20(33-3)24(34-4)26(35-5)22(18)23-19(14-21-25(27(23)36-6)38-15-37-21)28(30(16,2)32)39-29(31)17-10-8-7-9-11-17/h7-11,13-14,16,28,32H,12,15H2,1-6H3/t16-,28-,30-/m0/s1
Canonical SMILES:
CC1CC2=CC(=C(C(=C2C3=C(C4=C(C=C3C(C1(C)O)OC(=O)C5=CC=CC=C5)OCO4)OC)OC)OC)OC
1.Drug-drug interation prediction between ketoconazole and anti-liver cancer drug Gomisin G.
Xiaoyang L1, Chenming N2, Chengqing L3, Tao L4. Afr Health Sci. 2015 Jun;15(2):590-3. doi: 10.4314/ahs.v15i2.35.
BACKGROUND: Gomisin G, isolated from herb Schisandra chinensis, exhibits anti-tumor activities. Therefore, Gomisin G is a drug candidate for anti-liver cancer therapy.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related HIV Products


CAS 333352-59-3 NBD-557

NBD-557
(CAS: 333352-59-3)

NBD-557 is a N-phenyl-N'-(2,2,6,6-tetramethyl-piperidin-4-yl)-oxalamide analog, a novel class of human immunodeficiency virus type 1 (HIV-1) entry inhibitors th...

CAS 1180-71-8 Limonin

Limonin
(CAS: 1180-71-8)

Limonin is a triterpenoid enriched in citrus fruits, which has antivirus and antitumor ability.

CAS 3056-17-5 Stavudine (d4T)

Stavudine (d4T)
(CAS: 3056-17-5)

Stavudine (d4T) is a nucleoside analog reverse transcriptase inhibitor (NARTI) active against HIV.

CAS 157810-81-6 Indinavir sulfate

Indinavir sulfate
(CAS: 157810-81-6)

Indinavir is a protease inhibitor used as a component of highly active antiretroviral therapy to treat HIV infection and AIDS. It inhibits the HIV-1 protease wi...

CAS 136470-78-5 Abacavir

Abacavir
(CAS: 136470-78-5)

Abacavir sulfate is a Nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS.

CAS 143491-57-0 Emtricitabine

Emtricitabine
(CAS: 143491-57-0)

Emtricitabine moderately reduces hepatocyte proliferation independent of effects on mtDNA in HepG2 human hepatoma cells.

CAS 697761-98-1 Elvitegravir

Elvitegravir
(CAS: 697761-98-1)

Elvitegravir (EVG, JTK-303/GS-9137) is an HIV integrase inhibitor for HIV-1 IIIB, HIV-2 EHO and HIV-2 ROD with IC50 of 0.7 nM, 2.8 nM and 1.4 nM, respectively.

CAS 431980-38-0 RN-18

RN-18
(CAS: 431980-38-0)

RN-18, a selective inhibitor of virion infectivity factor (Vif) APOBEC interactions and HIV-1 replication (IC50= 6 μM in nonpermissive H9 cells), antagonizes Vi...

CAS 379270-38-9 GS-7340 fumarate

GS-7340 fumarate
(CAS: 379270-38-9)

Tenofovir alafenamide fumarate, also known as Tenofovir alafenamide hemifumarate; TAF, GS-7340, is a nucleotide reverse transcriptase inhibitor and a novel pro...

BMS-663749
(CAS: 864953-33-3)

BMS-663749 is HIV-1 attachment inhibitor.

CAS 1415559-43-1 CDK9-IN-1

CDK9-IN-1
(CAS: 1415559-43-1)

Among CDKs, CDK9 is a validated pathological target in HIV infection, inflammation and cardiac hypertrophy; however selective CDK9 inhibitors are still not avai...

D77
(CAS: 497836-10-9)

D77 is anti-HIV-1 inhibitor, which inhibits HIV-1(IIIB) replication (EC50=23.8 μM)

CAS 161814-49-9 Amprenavir

Amprenavir
(CAS: 161814-49-9)

Amprenavir promotes the specific interactions between the nuclear receptor pregnane X receptor (PXR) and the coactivators SRC-1 and PBP.

CAS 376348-65-1 Maraviroc

Maraviroc
(CAS: 376348-65-1)

Selective CCR5 antagonist

CAS 226700-81-8 Fosamprenavir Calcium Salt

Fosamprenavir Calcium Salt
(CAS: 226700-81-8)

HIV protease inhibitor; water soluble prodrug of amprenavir.

CAS 62956-48-3 Gomisin G

Gomisin G
(CAS: 62956-48-3)

Gomisin G, carboxylic acid with additional oxygen functions, exhibited the most potent anti-HIV activity with EC50 and therapeutic index (TI) values of 0.006 mi...

CAS 198904-31-3 Atazanavir

Atazanavir
(CAS: 198904-31-3)

Atazanavir is a novel and potent azapeptide protease inhibitor that specifically inhibits the human immunodeficiency virus type 1 (HIV-1) protease enzyme with i...

CGP 57813
(CAS: 150608-41-6)

CGP 57813 has been found to be a HIV-1 protease inhibitor that has been once developed by Novartis.

CAS 159989-64-7 Nelfinavir

Nelfinavir
(CAS: 159989-64-7)

Nelfinavir is a HIV protease inhibitor; antiretroviral; and anti-tumor agent.

CAS 518048-05-0 Raltegravir

Raltegravir
(CAS: 518048-05-0)

Raltegravir (MK-0518) is a potent integrase (IN) inhibitor for WT and S217Q PFV IN with IC50 of 90 nM and 40 nM, respectively.

Chemical Structure

CAS 62956-48-3 Gomisin G

Quick Inquiry

Verification code

Featured Items