GNF1331 - CAS 603101-22-0
Catalog number:
603101-22-0
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H20N6O2S2
Molecular Weight:
440.54
COA:
Inquire
Targets:
Porcupine
Description:
GNF1331 is a potent, selective and orally bioavailable porcupine (PORCN) inhibitor with IC50 value of 12 nM. It plays a critical role in multiple cancers, such as cutaneous squamous cell carcinoma (SCC), colorectal cancer and breast cancer.
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Purity:
98%
Appearance:
Solid powder
Synonyms:
N-(6-methoxy-1,3-benzothiazol-2-yl)-2-[(4-propyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide;GNF-1331
Solubility:
Soluble in DMSO, not in water
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
GNF1331 plays a critical role in multiple cancers, such as cutaneous squamous cell carcinoma (SCC), colorectal cancer and breast cancer.
Quality Standard:
In-house standard
Quantity:
Milligrams-Grams
Density:
1.44±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
InChIKey:
JIUFLMSAFMXEEC-UHFFFAOYSA-N
InChI:
InChI=1S/C20H20N6O2S2/c1-3-10-26-18(13-6-8-21-9-7-13)24-25-20(26)29-12-17(27)23-19-22-15-5-4-14(28-2)11-16(15)30-19/h4-9,11H,3,10,12H2,1-2H3,(H,22,23,27)
Canonical SMILES:
CCCN1C(=NN=C1SCC(=O)NC2=NC3=C(S2)C=C(C=C3)OC)C4=CC=NC=C4
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