|Description||GKT137831 attenuates hypoxia-induced H(2)O(2) release, cell proliferation, and TGF-β1 expression and blunted reductions in PPARγ in HPAECs and HPASMCs.|
BPH-652, also known as BMS-187745, has been found to be a SQS inhibitor that could probably be effective against S. aureus infections.
Extract from Carthamin, widely used for the treatment of acute ischemic stroke by acting directly on BV2 microglia.
Sufugolix, also known as TAK-013, is a highly potent, non-peptide and orally available luteinizing hormone-releasing hormone (LHRH) receptor antagonist with an ...
Sipeimine, a natural product isolated from Fritillaria ussuriensis., can make Kaba cholinergic induced contraction of tracheal strips of the dose-response curve...
PD-116779 is a novle antitumor antibiotic belonging the benz[a]anthraquinone class.
Salvianolic acid B
Source from root of Salvia miltiorrhiza Bge. It showed a protective action against the ischemia-reperfusion induced injury in rat brain by reducing lipid peroxi...
Carzenide, a Sulfanilamide derivative, could be used as an intermediate to synthesize sorts of pharmaceuticals like carbonic anhydrase inhibitors.
Succinyl phosphonate was found to be effective inhibitors of alpha-ketoglutarate oxidative decarboxylation, catalyzed by both muscle and bacterial alpha-ketoglu...
UK-371804 is a novel and selective inhibitors of urokinase plasminogen activator (uPA). UK-371804 exhibits excellent enzyme potency (Ki 10 nM) and selectivity p...
Fenbufen is a non-steroidal anti-inflammatory synthetic active reagent.
Schisandrol B is one of its major active constituents of traditional hepato-protective Chinese medicine, Schisandra sphenanthera.
HSR60716071, a novel pyrazinecarboxamide derivative, exhibits potent inhibition of the IgE-mediated passive cutaneous anaphylaxis (PCA) in rats on oral administ...
Articaine is a dental amide-type local anesthetic. It is the most widely used local anesthetic in a number of European countries and is available in many countr...
Cimiracemoside D is a natural product found in Actaea racemosa with unknown details.
sn-Glycero-3-phosphocholine (Choline Alfoscerate) is a phospholipid; precursor in choline biosynthesis. sn-Glycero-3-phosphocholine is an intermediate in catabo...
Guanoxyfen sulfate is an inhibitor of vasoconstrictor responses to sympathetic nerve stimulation. It could potentiate the actions of adrenaline and noradrenalin...
Chromocarb is a vasoprotectant.
KYP-2047 is a selective Prolyl oligopeptidase inhibitor. And it is also known as prolyl endopeptidase. KYP-2047 can reduce α-synuclein protein levels and aggreg...
ON-013100, a cell cycle inhibitor, altered the growth and cell cycle status of MCL lines and potently inhibited the expression of several important molecules, i...
GAT-100, an indole derivative, has been found to be a negative allosteric modulator that could be used as a covalent probe in studying of the binding motifs of ...