| Molecular Formula: | |
|---|---|
| Molecular Formula | C23H33N7O5S.C6H6O3S |
| Molecular Weight: | |
| Molecular Weight | 677.79 |
| COA: | |
| COA | Inquire |
| Targets: | |
| Targets | Phosphodiesterase (PDE) |
| Description: | |
| Description | Gisadenafil besylate is a potent PDE5 inhibitor (IC50 = 1.23 nM) with >100-fold selectivity for PDE5 over PDE6. Gisadenafil besylate inhibits the breakdown of cyclic phosphodiester secondary messenger molecules. |
| Brife Description: | |
|---|---|
| Brife Description | PDE5 inhibitor |
| Purity: | |
| Purity | ≥99% by HPLC |
| Synonyms: | |
| Synonyms | UK 369003; UK369003; UK-369003; 5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]-3-pyridinyl]-3-ethyl-2,6-dihydro-2-(2-methoxyethyl)-7H-pyrazolo[4,3-d]pyrimidin-7-one benzenesulfonate |
| MSDS: | |
| MSDS | Inquire |
| InChIKey: | |
|---|---|
| InChIKey | STFRDYSZKVPPQF-UHFFFAOYSA-N |
| InChI: | |
| InChI | InChI=1S/C23H33N7O5S.C6H6O3S/c1-5-18-19-20(27-30(18)12-13-34-4)22(31)26-21(25-19)17-14-16(15-24-23(17)35-7-3)36(32,33)29-10-8-28(6-2)9-11-29;7-10(8,9)6-4-2-1-3-5-6/h14-15H,5-13H2,1-4H3,(H,25,26,31);1-5H,(H,7,8,9) |
| Canonical SMILES: | |
| Canonical SMILES | CCC1=C2C(=NN1CCOC)C(=O)N=C(N2)C3=CC(=CN=C3OCC)S(=O)(=O)N4CCN(CC4)CC.C1=CC=C(C=C1)S(=O)(=O)O |
Siguazodan
(CAS: 115344-47-3)
Siguazodan is a selective phosphodiesterase 3 (PDE3) inhibitor (IC50 = 117 nM). Siguazodan acts as a potent vasodilator.
Bay 60-7550
(CAS: 439083-90-6)
Bay 60-7550 is a potent PDE2 inhibitor. It is 50-fold more selective for PDE2 compared to PDE1 and greater than 100-fold selective compared to PDE5 PDE3B, PDE4B...
Cilostamide
(CAS: 68550-75-4)
Cilostamide is a selective and specific inhibitor of type III phosphodiesterase (PDE3). It shows moderate selectivity for PDE3A isozyme and PDE3B. It increases ...
TP-10
(CAS: 898563-00-3)
TP-10 is a PDE10A inhibitor with IC50 of 0.8 nM. It has extremely potent PDE10A inhibitory activity and high selectivity against other PDEs. It is active in the...
(R)-(-)-Rolipram
(CAS: 85416-75-7)
(R)-(-)-Rolipram is a potent and cAMP-specific PDE4 inhibitor. It is 2.5-fold more potent than (+)-rolipram in inhibiting membrane-bound PDE 4.
Ibudilast
(CAS: 50847-11-5)
Ibudilast is a nonselective inhibitor of cyclic nucleotide phosphodiesterase (PDE) which has been marketed for treating asthma. It crosses the blood-brain barri...
Cilostazol
(CAS: 73963-72-1)
Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake.
Chemical Structure
