1. Simultaneous Determination of a Broad Spectrum of Nonconjugated Xenobiotics by High-Performance Liquid Chromatography–Tandem Mass Spectrometry
M. A. Dikunets, S. A. Appolonova, and G. M. Rodchenkov. Journal of Analytical Chemistry, 2009, Vol. 64, No. 8, pp. 832–842
The goal of this work was to develop a procedure for the simultaneous determination of corticosteroids, diuretics, CNS stimulants, narcotics, and a number of anabolic steroids in humane urine, which allowed one to reduce the number of steps and the cost of antidoping control per sample. The anabolic steroids oxandrolone, trenbolone, gestrinone, and tetrahydroxygestrinone were selected, because they are low-volatile or decompose in derivatization; therefore, they had high detection limits in GC–MS.