|Description||Genz-123346 is an inhibitor of GL1 synthase that blocks the conversion of ceramide to GL1. It does not inhibit α-glucosidase or glucocerebrosidase. It lowered glucose and A1C levels and improved glucose tolerance in the Zucker diabetic fatty rat.|
Faropenem potassium is an orally active beta-lactam antibiotic. It is a prodrug of Faropenem and belongs to the penem group. It is resistant to some forms of ex...
Bevantolol is a beta-1 adrenoceptor antagonist has been shown to be as effective as other beta blockers for the treatment of angina pectoris and hypertension
Exherin, also known as ADH-1, is a small, cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 select...
Idramantone, an immune agonist, can be used to prepare adamantane substituted guanylhydrazones.
Tuftsin diacetate is a macrophage/microglial activator.
Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM.
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1) (IC50= 52 nM).
Dimesna is a synthetic derivative of dithio-ethane sulfonate with uroprotective properties. In the kidney, dimesna undergoes reduction to the free thiol compoun...
ONO EI-601, a sulfonylamine derivative, is one metabolite of ONO-5046 which is a neutrophil elastase inhibitor that could be effective against acute lung injury...
GSK376501A is a bio-active chemical compound used for the treatment of type 2 diabetes and hypercholesterolemia. It was developed by GlaxoSmithKline and was onc...
Trodusquemine, also called as MSI-1436 or Aminosterol-1436, with the potential to treat type 2 diabetes and obesity, it is a non-competitive cholestane inihbito...
UK 34787 is a thromboxane inhibitor，but no detailed information has been published yet.
Methyl linolenate, a polyunsaturated fattly acid (PUFA), is an autoxidation product that is used to study the mechanisms and prevention of oxidation/peroxidatio...
This active molecular is an potential cognitive enhancer originated by Bristol-Myers Squibb. Mechanism of Action is not identified. Bmy 21502 is also a nootropi...
Chitinase-IN-1 is a insect chitinase and N- acetyl hexosaminidase inhibitor and pesticide; 50 uM/20uM compound concentration's inhibitory percentage are 75%...
This active moleculr is a Os(II) anticancer drug candidate. It can generate reactive oxygen species and disrupt the redox balance in cancer cells. Using FY26 an...
Rabies Virus Glycoprotein, a 29-amino-acid cell penetrating peptide derived from a rabies virus glycoprotein, is only structural protein of the virus that induc...
Aloin B is one isomer of Aloin; Aloin is a physiologically active anthraquinone present in aloe.
PD 138142 is a water soluble Sterol O-acyltransferase inhibitor. Triacylglycerol secretion is decreased in the presence of PD-138142-15. Preclinical development...