Gedunin - CAS 2753-30-2
Catalog number: 2753-30-2
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C28H34O7
Molecular Weight:
482.57
COA:
Inquire
Targets:
Hsp90
Description:
Gedunin is a naturally occurring Hsp90 inhibitor. Induces Hsp90-dependent client protein degradation and displays antiproliferative activity in vitro (IC50 values are 3.22, 8.84 and 16.8 μM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively). It also exhibits antimalarial activity against P. falciparum (IC50 values are 0.14 and 3.1 μM in parasite development and [3H]-hypoxanthine uptake assays respectively).
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Brife Description:
Gedunin is a Hsp90 inhibitor, exhibits anticancer and antimalarial activity.
Purity:
>98%
Appearance:
Solid powder
Solubility:
DMSO: 100 mg/mL; Ethnaol: 10mg/mL with gentle warming
Storage:
Store at + 4oC
MSDS:
Inquire
Quality Standard:
In-house
Quantity:
Grams-Kilos
InChIKey:
YJXDGWUNRYLINJ-BHAPSIHVSA-N
InChI:
InChI=1S/C28H34O7/c1-15(29)33-20-13-18-24(2,3)19(30)8-10-25(18,4)17-7-11-26(5)21(16-9-12-32-14-16)34-23(31)22-28(26,35-22)27(17,20)6/h8-10,12,14,17-18,20-22H,7,11,13H2,1-6H3/t17-,18+,20-,21+,22-,25-,26+,27+,28-/m1/s1
Canonical SMILES:
CC(=O)OC1CC2C(C(=O)C=CC2(C3C1(C45C(O4)C(=O)OC(C5(CC3)C)C6=COC=C6)C)C)(C)C
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CAS 2753-30-2 Gedunin

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