GDC-0994 - CAS 1453848-26-4
Catalog number: 1453848-26-4
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
Inquire
Targets:
ERK
Description:
GDC-0994, also known as RG7842, is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, GDC-0994 inhibits both ERK phosphorylation and activation of ERK-mediated signal transduction pathways. This prevents ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.
Publictions citing BOC Sciences Products
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Appearance:
Solid powder
Synonyms:
GDC-0994; GDC0994; GDC 0994; RG7842; RG-7842; RG 7842.
MSDS:
Inquire
Current Developer:
Genentech
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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CAS 1453848-26-4 GDC-0994

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