GC376 sodium - CAS 1416992-39-6
Catalog number: B0084-007378
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C21H30N3NaO8S
Molecular Weight:
507.53
COA:
Inquire
Targets:
Others
Description:
GC376 is a 3CLpro inhibitor which is previously reported to be active against the 3CLpro of multiple coronaviruses, including SARS-CoV, but with highest potency against FIPV in cell culture. GC376 inhibits the replication of viruses TGEV, FIPV and PTV with IC50 values of 0.15, 0.2 and 0.15 μM.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-007378 10 mg $199 In stock
B0084-007378 50 mg $299 In stock
B0084-007378 100 mg $499 In stock
Bulk Inquiry
Brife Description:
3CLpro inhibitor
Related CAS:
1417031-79-8 (free acid)
Synonyms:
(2S)-1-hydroxy-2-[[(2S)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonate sodium
Solubility:
Soluble in DMSO.
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
BSPJDKCMFIPBAW-JPBGFCRCSA-N
InChI:
InChI=1S/C21H31N3O8S.Na/c1-13(2)10-16(24-21(28)32-12-14-6-4-3-5-7-14)19(26)23-17(20(27)33(29,30)31)11-15-8-9-22-18(15)25;/h3-7,13,15-17,20,27H,8-12H2,1-2H3,(H,22,25)(H,23,26)(H,24,28)(H,29,30,31);/q;+1/t15?,16-,17-,20?;/m0./s1
Canonical SMILES:
CC(C)CC(C(=O)NC(CC1CCNC1=O)C(O)S(=O)(=O)O)NC(=O)OCC2=CC=CC=C2.[Na+]
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products


CAS 149682-77-9 Talabostat

Talabostat
(CAS: 149682-77-9)

Talabostat, also called as PT100 or Val-boroPro, is a potent, nonselective and orally available dipeptidyl peptidase IV(DPP-IV) inhibitor (Ki= 0.18 nM) with ant...

CAS 1002295-95-5 Camstatin

Camstatin
(CAS: 1002295-95-5)

Camstatin, an analog of PEP-19, has been found to have enhanced activities binding to and antagonism of calmodulin.

CAS 1216744-19-2 GSK4112

GSK4112
(CAS: 1216744-19-2)

GSK 4112, a kind of synthetic agonist of REV-ERBα, could suppress the expression of sorts of genes involved in gluconeogenesis. IC50: 0.4 μM (EC50).

CAS 82351-05-1 Lvguidingan

Lvguidingan
(CAS: 82351-05-1)

Lvguidingan is an antiepileptic drug.

CAS 900510-03-4 PF-3274167

PF-3274167
(CAS: 900510-03-4)

PF-3274167, also known as PF-03274167 or PF-327,4167, is a potent and selective, high-affinity nonpeptide oxytocin receptor antagonist.

CAS 18194-25-7 DLPC

DLPC
(CAS: 18194-25-7)

DLPC is a selective agonist of the orphan nuclear receptor LRH-1 (liver receptor homolog-1, NR5A2) in vitro with antidiabetic activity. It causes an increase of...

Presatovir
(CAS: 1353625-73-6)

Presatovir is a viral fusion protein inhibitor originated by Gilead Sciences with EC50 value of 0.43 nM. GS-5806 can inhibit a broad range of respiratory syncyt...

CAS 135463-81-9 Coluracetam

Coluracetam
(CAS: 135463-81-9)

MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholin...

CAS 78510-31-3 PSB 069

PSB 069
(CAS: 78510-31-3)

PSB 069 is a non-selective inhibitor of nucleoside triphosphate diphosphohydrolases 1,2,3 (NTPDases 1,2,3) (Ki = 15.7, 18.0, 16.4 µM, respectively). It was repo...

CAS 3624-96-2 Bialamicol hydrochloride

Bialamicol hydrochloride
(CAS: 3624-96-2)

Bialomicol is a synthetic bio-active chemical.

CAS 176975-26-1 Izonsteride

Izonsteride
(CAS: 176975-26-1)

Izonsteride, a benzothiazolyl derivative, has been found to be a cholestenone 5-alpha reductase inhibitor that was once studied in prostate cancer and probably ...

CAS 1203956-47-1 11β-HSD1-IN-1

11β-HSD1-IN-1
(CAS: 1203956-47-1)

11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1) (IC50= 52 nM).

AT-584
(CAS: 16810-17-6)

AT-584, an azoniatricyclo compound, could have potential biological activity in pharmaceutical studies.

CAS 19309-14-9 Cardamonin

Cardamonin
(CAS: 19309-14-9)

Cardamonin is a naturally occuring chalcone initially isolated from the seeds of Amomum subulatum and subsequently from other zingiberous plant species. Cardamo...

CAS 31137-74-3 SYM 2081

SYM 2081
(CAS: 31137-74-3)

SYM 2081 is a highly selective and potent kainate receptor agonist with IC50 for 35 nM, which is almost 200- and 3,000-fold selectivity over NMDA and AMPA recep...

CAS 56296-18-5 DREADD agonist 21

DREADD agonist 21
(CAS: 56296-18-5)

DREADD agonist 21 has been found to be an agonist of hM3Dq with high selectivity.

CAS 1094-61-7 β-Nicotinamide Mononucleotide

β-Nicotinamide Mononucleotide
(CAS: 1094-61-7)

β-Nicotinamide mononucleotide, a major product of extracellular NAMPT reaction, could ameliorate glucose intolerance and also increase hepatic insulin sensitivi...

CAS 1083-57-4 Bucetin

Bucetin
(CAS: 1083-57-4)

Bucetin, a phenacetin analog, has antipyretic and analgesic effect. It has been discontinued for showing renal toxicity.

CAS 161416-61-1 ABT 089 dihydrochloride

ABT 089 dihydrochloride
(CAS: 161416-61-1)

ABT 089 dihydrochloride is a selective α4β2 nicotinic acetylcholine receptor partial agonist (Ki = 16 nM) with >1000-fold and >10,000-fold selectivity for α4β2 ...

CAS 189197-69-1 Ro 48-8071 fumarate

Ro 48-8071 fumarate
(CAS: 189197-69-1)

Ro 48-8071 is an orally active cholesterol synthesis inhibitor or a 2,3-oxidosqualene:lanosterol cyclase (OSC) inhibitor. OSC (EC 5.4.99.7) represents a unique ...

Chemical Structure

CAS 1416992-39-6 GC376 sodium

Quick Inquiry

Verification code

Featured Items