Gatifloxacin mesylate - CAS 316819-28-0
Catalog number: 316819-28-0
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H26FN3O7S
Molecular Weight:
471.5
COA:
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Targets:
Antibacterial
Description:
Gatifloxacin (mesylate) is an antibiotic of the fourth-generation fluoroquinolone family, it inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.
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Purity:
>98%
Synonyms:
AM 1155 mesylate; BMS 206584-01 mesylate; PD 135432 mesylate
MSDS:
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1.Comprehensive evaluation of formulation factors for ocular penetration of fluoroquinolones in rabbits using cassette dosing technique.
Sharma C1, Biswas NR2, Ojha S3, Velpandian T2. Drug Des Devel Ther. 2016 Feb 22;10:811-23. doi: 10.2147/DDDT.S95870. eCollection 2016.
OBJECTIVE: Corneal permeability of drugs is an important factor used to assess the efficacy of topical preparations. Transcorneal penetration of drugs from aqueous formulation is governed by various physiological, physiochemical, and formulation factors. In the present study, we investigated the effect of formulation factors like concentration, pH, and volume of instillation across the cornea using cassette dosing technique for ophthalmic fluoroquinolones (FQs).
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CAS 316819-28-0 Gatifloxacin mesylate

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