|Description||Gamabufotalin is a major bufadienolide of Chansu and has been used for cancer therapy due to its desirable metabolic stability and less adverse effect.|
3,3,5-Triiodo-L-thyronine(T3), an active metabolite of Thyroxine, could be effective in agonizing both thyroid hormone receptors TRα and TRβ so that might help ...
Arenobufagin is a bufanolide steroid isolated from the Argentine toad Bufo arenarum. This compound exhibits anticancer chemotherapeutic and anti-angiogenic prop...
AVN-944 (VX-944) is an orally available, synthetic small molecule with potential antineoplastic activity. AVN944 inhibits inosine monosphosphate dehydrogenase (...
LB-100 is a water solubleprotein phosphatase 2A (PP2A)inhibitor(IC50= 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells) and enhanced the effects of sorafenib in H...
Salvianolic acid B
Source from root of Salvia miltiorrhiza Bge. It showed a protective action against the ischemia-reperfusion induced injury in rat brain by reducing lipid peroxi...
Pozanicline, a pyridine derivative, has been found to be a nicotinic receptor modulator that was once studied in Alzheimer's disease as a neuroprotective agent.
(R)-(-)-Modafinic acid(Armodafinic acid) is the major metabolite of Modafinil(HY-10521A), which is a central nervous system vigilance promoting agent, which pos...
Bromhexine is a mucolytic (expectorant) agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. In addition, bromhexine ...
Isochlorogenic acid C
Source from The herbs of Laggera alata, Isochlorogenic acid C is a selective inhibitor of human immunodeficiency virus type 1 integrase.
Anisindione, an anticoagulant, could avoid the generation of active procoagulation factors and sorts of proteins in the liver.
Extract from Carthamin, widely used for the treatment of acute ischemic stroke by acting directly on BV2 microglia.
Hemoglobin Modulators-1, a substituted benzaldehyde compound that can modulate sickle hemoglobin (HbS) for treatment of disorders.
Glucagon, a peptide compound, is effective in increasing the glucose concentration in bloodstream and could be released by pancrea α cells.
ATR-101 is a selective Acetyl CoA C-acetyltransferase inhibitor. ATR-101 is uniquely distributed to adrenal tissues and inhibition of adrenal ACAT1 by ATR-101 d...
Vinorelbine, also called Navelbine, a 5′NOR semisynthetic vinca alkaloid which arrests tumor cell growth in metaphase by binding to tubulin and preventing form...
AP1903 is a lipid-permeable tacrolimus analogue with homodimerizing activity. Dimerizer drug AP1903 homodimerizes an analogue of human protein FKBP12 (Fv) which...
MC-Val-Cit-PAB-OH, a kind of ADC peptide linker, could be used in the formation of ADC conjugate and be significant in anticancer studies.
BIBF 1202 is the major in-vivo metabolite of BIBF 1120, which is an oral triple angiokinase inhibitor targeting VEGFR, PDGFR, FGFR. It is a related compound of ...
Levetiracetam is an anticonvulsant medication used to treat epilepsy.
Tacrine is a centrally acting anticholinesterase and indirect cholinergic agonist for the palliative treatment of mild to moderate dementia of the Alzheimer's t...