Gabapentin hydrochloride - CAS 60142-95-2
Catalog number:
60142-95-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C9H17NO2.HCl
Molecular Weight:
207.7
COA:
Inquire
Targets:
Calcium Channel
Description:
Gabapentin HCl is a GABA analogue.Originally it was developed to treat epilepsy, and is currently used to relieve neuropathic pain and restless leg syndrome.
Publictions citing BOC Sciences Products
  • >> More
Purity:
>98%
MSDS:
Inquire
1.Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia.
Kim SC1, Landon JE2, Lee YC3. Arthritis Res Ther. 2015 Jan 28;17:18. doi: 10.1186/s13075-015-0530-8.
INTRODUCTION: Several pharmacologic treatments are available for fibromyalgia, but little is known about the comparative effectiveness of these treatments on health care utilization.
2.Chemotherapy-induced peripheral neuropathy in patients treated with taxanes and platinum derivatives.
Ewertz M1, Qvortrup C, Eckhoff L. Acta Oncol. 2015 May;54(5):587-91. doi: 10.3109/0284186X.2014.995775. Epub 2015 Mar 9.
BACKGROUND: Chemotherapy with taxanes and platinum compounds has resulted in substantial survival benefits both in adjuvant and metastatic settings. However, as a side effect, such chemotherapy may cause peripheral neuropathy (CIPN) which may result in discontinuation of treatment, and if it persists after treatment completion, has a negative impact on quality of life (QoL).
3.Dystonia.
Snaith A1, Wade D. BMJ Clin Evid. 2014 Feb 28;2014. pii: 1211.
INTRODUCTION: Dystonia is usually a lifelong condition with persistent pain and disability. Focal dystonia affects a single part of the body; generalised dystonia can affect most or all of the body. It is more common in women, and some types of dystonia are more common in people of Ashkenazi descent.
4.Nefopam Hydrochloride: A Fatal Overdose.
Seetohul LN1, De Paoli G2, Drummond G2, Maskell PD3. J Anal Toxicol. 2015 Jul-Aug;39(6):486-9. doi: 10.1093/jat/bkv036. Epub 2015 Apr 7.
Nefopam is a non-opiate analgesic commonly used for the treatment of moderate to severe pain. A case of a 37-year-old male who was found dead in the morning is presented. An autopsy was performed and femoral venous blood, heart blood, urine, and vitreous humor were submitted for toxicological analysis. A general drug screen detected the presence of nefopam, caffeine, nicotine, citalopram, gabapentin, amitriptyline, diazepam and paracetamol in cardiac blood. Nefopam was quantitated by high-performance liquid chromatography with diode-array detection. Nefopam was found at the following concentrations: 13.6 mg/L in unpreserved femoral blood; 14.7 mg/L in preserved (fluoride-oxalate) femoral blood; 21.2 mg/L in unpreserved cardiac blood and 4.5 mg/L in preserved vitreous. Citalopram was present at a concentration of 0.7 mg/L (femoral blood) and 0.9 mg/L (cardiac blood). Ethanol analyzed by headspace gas chromatography (GC-FID) was detected in preserved (fluoride-oxalate) vitreous (14 mg/100 mL) and preserved (fluoride-oxalate) urine 50 mg/100 mL.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Calcium Channel Products


CAS 14663-23-1 Dantrolene Sodium

Dantrolene Sodium
(CAS: 14663-23-1)

Dantrolene Sodium, an inhibitor of calcium channel proteins that markedly suppresses the release of calcium previously sequestered by skeletal, but not cardiac,...

CAS 103890-78-4 Lacidipine

Lacidipine
(CAS: 103890-78-4)

Lacidipine (Lacipil, Motens) is a L-type calcium channel blocker. Lacidipine (Lacipil, Motens) works by relaxing and opening up the blood vessels.

GV-58
(CAS: 1402821-41-3)

GV-58, a pupin derivative, has been found to be a P/Q-type Ca²⁺-channel agonist that could be used to against neuromuscular weakness. IC50: 7.21/8.81 uM (N-type...

CAS 75695-93-1 Isradipine

Isradipine
(CAS: 75695-93-1)

Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure.

CAS 610300-07-7 Imagabalin

Imagabalin
(CAS: 610300-07-7)

Imagabalin acts as a ligand for the α2δ subunit of the voltage-dependent calcium channel, which has some selectivity for the α2δ1 subunit over α2δ2. It has anxi...

CAS 116644-53-2 Mibefradil

Mibefradil
(CAS: 116644-53-2)

Mibefradil, a calcium channel blocker, has modest selectivity for T-type Ca2+ channels so that could be used in the treatment of sorts of cardiovascular disease...

Evenamide
(CAS: 1092977-61-1)

Evenamide is a selective voltage-gated sodium and​/or calcium channel modulator, including subtypes Nav1.3, Nav1.7, and Nav1.8. It may be potentia useful in pre...

CAS 111011-76-8 Efonidipine hydrochloride monoethanolate

Efonidipine hydrochloride monoethanolate
(CAS: 111011-76-8)

The hydrochloride monoethanolate salt form of Efonidipine which has been launched for hypertension and discontinued for cerebrovascular disorders.

CAS 54527-84-3 Nicardipine Hydrochloride

Nicardipine Hydrochloride
(CAS: 54527-84-3)

Nicardipine is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders.

CAS 60142-95-2 Gabapentin hydrochloride

Gabapentin hydrochloride
(CAS: 60142-95-2)

Gabapentin HCl is a GABA analogue.Originally it was developed to treat epilepsy, and is currently used to relieve neuropathic pain and restless leg syndrome.

UK-1745
(CAS: 170684-14-7)

UK-1745, an indole derivative, has been found to be a Calcium channel antagonist that was once studied in the treatment of arrhythmias as well as heart failure.

Etripamil
(CAS: 1593673-23-4)

Etripamil, a benzoates derivative, has been found to be a calcium channel antagonist that could be used against hypertension and arrhythmic. It is currently und...

CAS 111011-63-3 EFONIDIPINE

EFONIDIPINE
(CAS: 111011-63-3)

Efonidipine could be effective in the treatment of cardiovascular disease as a blocker of T-type and L-type calcium channels. It could also present as the hydro...

CAS 75530-68-6 Nilvadipine

Nilvadipine
(CAS: 75530-68-6)

Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM.

CAS 298-57-7 Cinnarizine

Cinnarizine
(CAS: 298-57-7)

Cinnarizine, with antiallergic and anti-vasoconstricting activity, is a calcium channel blocker to treat cerebral apoplexy, post-trauma cerebral symptoms, and c...

Ca2+ Channel Agonist 1
(CAS: 1402821-24-2)

A Ca2+ Channel Agonist that selectively acting on N-type Ca2+ channel and also be found to restrain the cdk activity at some extent. IC50: 14.23 uM (EC50, Ca2+ ...

CAS 108852-42-2 YS-201

YS-201
(CAS: 108852-42-2)

YS-201, also known as Diperdipine, is a dihydropyridine-type calcium channel antagonist potentially for the treatment of angina pectoris and hypertension.

S(-)-BAY K 8644
(CAS: 98625-26-4)

S(-)-BAY K 8644 is an activator of voltage-sensitive L-type calcium channels with positive inotropic, vasoconstrictive and behavioral effects in vivo. It is the...

CAS 42399-41-7 Diltiazem

Diltiazem
(CAS: 42399-41-7)

Diltiazem is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia as a p...

CAS 89226-75-5 Manidipine 2HCl

Manidipine 2HCl
(CAS: 89226-75-5)

Manidipine 2HCl, a HCl salt form of Manidipine, is a calcium channel blocker with IC50 of 2.6 nM.

Chemical Structure

CAS 60142-95-2 Gabapentin hydrochloride

Quick Inquiry

Verification code

Featured Items