Gabapentin hydrochloride - CAS 60142-95-2
Catalog number: 60142-95-2
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C9H17NO2.HCl
Molecular Weight:
207.7
COA:
Inquire
Targets:
Calcium Channel
Description:
Gabapentin HCl is a GABA analogue.Originally it was developed to treat epilepsy, and is currently used to relieve neuropathic pain and restless leg syndrome.
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Purity:
>98%
MSDS:
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1.Patterns of health care utilization related to initiation of amitriptyline, duloxetine, gabapentin, or pregabalin in fibromyalgia.
Kim SC1, Landon JE2, Lee YC3. Arthritis Res Ther. 2015 Jan 28;17:18. doi: 10.1186/s13075-015-0530-8.
INTRODUCTION: Several pharmacologic treatments are available for fibromyalgia, but little is known about the comparative effectiveness of these treatments on health care utilization.
2.Chemotherapy-induced peripheral neuropathy in patients treated with taxanes and platinum derivatives.
Ewertz M1, Qvortrup C, Eckhoff L. Acta Oncol. 2015 May;54(5):587-91. doi: 10.3109/0284186X.2014.995775. Epub 2015 Mar 9.
BACKGROUND: Chemotherapy with taxanes and platinum compounds has resulted in substantial survival benefits both in adjuvant and metastatic settings. However, as a side effect, such chemotherapy may cause peripheral neuropathy (CIPN) which may result in discontinuation of treatment, and if it persists after treatment completion, has a negative impact on quality of life (QoL).
3.Dystonia.
Snaith A1, Wade D. BMJ Clin Evid. 2014 Feb 28;2014. pii: 1211.
INTRODUCTION: Dystonia is usually a lifelong condition with persistent pain and disability. Focal dystonia affects a single part of the body; generalised dystonia can affect most or all of the body. It is more common in women, and some types of dystonia are more common in people of Ashkenazi descent.
4.Nefopam Hydrochloride: A Fatal Overdose.
Seetohul LN1, De Paoli G2, Drummond G2, Maskell PD3. J Anal Toxicol. 2015 Jul-Aug;39(6):486-9. doi: 10.1093/jat/bkv036. Epub 2015 Apr 7.
Nefopam is a non-opiate analgesic commonly used for the treatment of moderate to severe pain. A case of a 37-year-old male who was found dead in the morning is presented. An autopsy was performed and femoral venous blood, heart blood, urine, and vitreous humor were submitted for toxicological analysis. A general drug screen detected the presence of nefopam, caffeine, nicotine, citalopram, gabapentin, amitriptyline, diazepam and paracetamol in cardiac blood. Nefopam was quantitated by high-performance liquid chromatography with diode-array detection. Nefopam was found at the following concentrations: 13.6 mg/L in unpreserved femoral blood; 14.7 mg/L in preserved (fluoride-oxalate) femoral blood; 21.2 mg/L in unpreserved cardiac blood and 4.5 mg/L in preserved vitreous. Citalopram was present at a concentration of 0.7 mg/L (femoral blood) and 0.9 mg/L (cardiac blood). Ethanol analyzed by headspace gas chromatography (GC-FID) was detected in preserved (fluoride-oxalate) vitreous (14 mg/100 mL) and preserved (fluoride-oxalate) urine 50 mg/100 mL.
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CAS 60142-95-2 Gabapentin hydrochloride

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