|Description||Gabapentin HCl is a GABA analogue.Originally it was developed to treat epilepsy, and is currently used to relieve neuropathic pain and restless leg syndrome.|
Mibefradil, a calcium channel blocker, has modest selectivity for T-type Ca2+ channels so that could be used in the treatment of sorts of cardiovascular disease...
NP-118809 is a N-type calcium channel blocker exhibits both anti-allodynic and anti-hyperalgesic activity in the spinal nerve ligation model of neuropathic pain...
Ca2+ Channel Agonist 1
A Ca2+ Channel Agonist that selectively acting on N-type Ca2+ channel and also be found to restrain the cdk activity at some extent. IC50: 14.23 uM (EC50, Ca2+ ...
Diltiazem HCl (Tiazac) is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.
Flunarizine is a selective calcium entry blocker, which has calmodulin binding properties and histamine H1 blocking activity. It may help to reduce the severity...
Fluspirilene, with antipsychotic activity, is a non-competitive antagonist of agonist-activated L-type calcium channels (IC50 = 0.03 µM). Fluspirilene is also a...
Gabapentin HCl is a GABA analogue.Originally it was developed to treat epilepsy, and is currently used to relieve neuropathic pain and restless leg syndrome.
GV-58, a pupin derivative, has been found to be a P/Q-type Ca²⁺-channel agonist that could be used to against neuromuscular weakness. IC50: 7.21/8.81 uM (N-type...
Flindokalner, an anxiolytic agent, is a positive modulator at neuronal Kv7 channels and calcium-activated K+ channels (BKCa) in HEK293 cells. Flindokalner can b...
The hydrochloride salt form of Fendiline, a benzenepropanamine derivative, has been found to be a calcium channel blocker and alpha2-adrenergic receptor antagon...
GAL-021 a novel intravenous BKCa-channel blocker potentially for the treatment of respiratory depression.
Cilnidipine is a unique L-type and N-type calcium channel blocker, used for high blood pressure treatment.
The hydrochloride salt form of Lercanidipine, a dihydropyridine derivative, could be used as an antihypertensive agent through influencing the L-type Ca2+ chann...
TTA-P2 is a selective T-type calcium channel blocker. It blocks T-type currents with an IC50 of 100 nM and stabilized channel in the inactive state in rats DRGs...
Dantrolene Sodium, an inhibitor of calcium channel proteins that markedly suppresses the release of calcium previously sequestered by skeletal, but not cardiac,...
Ranolazine 2HCl is a calcium uptake inhibitor via the sodium/calcium channal, used to treat chronic angina.
Diltiazem is a calcium channel antagonist. It can relax the smooth muscles in the walls of arteries, allow blood to flow more easily, and lower blood pressure. ...
Etripamil, a benzoates derivative, has been found to be a calcium channel antagonist that could be used against hypertension and arrhythmic. It is currently und...
(R)-(+)-Nor Verapamil Hydrochloride
This active molecular is a chiral metabolite of Verapamil which is a calcium channel blocker applicated in the treatment of hypertension, angina pectoris, cardi...
Bepridil is an amine Calcium channel antagonist that used to treat angina. But it is no longer sold in the United States. It may be a possible option in the tre...