|Description||Gabapentin HCl is a GABA analogue.Originally it was developed to treat epilepsy, and is currently used to relieve neuropathic pain and restless leg syndrome.|
CI 951 is a dihydronaphthyridine Ca2+ channel antagonist and it may be applicated for the treatment of focal cerebral ischemia. CI 951 has potential as a cerebr...
Huwentoxin XVI is a potent and selective N-type Ca2+ channel blocker (IC50 ~ 60 nM) with no inhibitory effect on T-type Ca2+ channels, K+ channels or Na+ channe...
(R)-(-)-BMS 204352 is the less active R-(-)-enantiomer of BMS-204352, which is a positive modulator at neuronal Kv7 channels and calcium-activated K+ channels (...
Ibutilide Fumarate is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset ...
Efonidipine hydrochloride monoethanolate
The hydrochloride monoethanolate salt form of Efonidipine which has been launched for hypertension and discontinued for cerebrovascular disorders.
Dantrolene Sodium, an inhibitor of calcium channel proteins that markedly suppresses the release of calcium previously sequestered by skeletal, but not cardiac,...
PD0176078 is a novel N-type calcium channel blocker.
Ned K, a NAADP inhibitor, prevents Ca2+ oscillations in rat cardiomyocytes in vitro during simulated ischemia and reperfusion, but exhibits no significant effec...
Osthole is a coumarin which is isolated from Cnidium monnieri (L.) Cusson. Osthole is a calcium channel modulator via inhibiting phosphodiesterases. It also reg...
RQ-00311651 is a novel T-type Ca channel inhibitor' which plays a role in neuropathic and visceral pain. RQ-00311651 notably inhibited T currents when tested at...
CALP2 is a cell-permeable calmodulin (CaM) antagonist binding to the EF-hand/Ca2+-binding site. CALP2 exhibits an inhibitory effect on CaM-dependant phosphodies...
Verapamil HCl is an L-type calcium channel blocker that is a class IV anti-arrhythmia agent.
Penfluridol (Semap, Micefal, Longoperidol) is a highly potent, first generation diphenylbutylpiperidine antipsychotic. It was discovered at Janssen Pharmaceutic...
cis-Ned 19 is a irreversible nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist, which inhibits Ca2+ release (IC50 = 800 nM) and [32P]NAADP bindin...
Evenamide is a selective voltage-gated sodium and/or calcium channel modulator, including subtypes Nav1.3, Nav1.7, and Nav1.8. It may be potentia useful in pre...
Bepridil is an amine Calcium channel antagonist that used to treat angina. But it is no longer sold in the United States. It may be a possible option in the tre...
Lavendustin C, also known as HDBA and NSC 666251, inhibits Ca2+/CaMKII (calmodulin kinase II) (IC50=0.2 μM), EGFR tyrosine kinase (IC50=44 nM) and SRC (IC50=0.5...
GAL-021 a novel intravenous BKCa-channel blocker potentially for the treatment of respiratory depression.
L-Phenylalanine, a α-amino acid, is an antagonist at α2δ calcium channels (Ki =980 nM).
Lercanidipine hydrochloride, a dihydropyridine compound, is a third generation calcium channel antagonist which shows longer duration of action of the past two ...