|Description||Gabapentin HCl is a GABA analogue.Originally it was developed to treat epilepsy, and is currently used to relieve neuropathic pain and restless leg syndrome.|
Dantrolene Sodium, an inhibitor of calcium channel proteins that markedly suppresses the release of calcium previously sequestered by skeletal, but not cardiac,...
Lacidipine (Lacipil, Motens) is a L-type calcium channel blocker. Lacidipine (Lacipil, Motens) works by relaxing and opening up the blood vessels.
GV-58, a pupin derivative, has been found to be a P/Q-type Ca²⁺-channel agonist that could be used to against neuromuscular weakness. IC50: 7.21/8.81 uM (N-type...
Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure.
Imagabalin acts as a ligand for the α2δ subunit of the voltage-dependent calcium channel, which has some selectivity for the α2δ1 subunit over α2δ2. It has anxi...
Mibefradil, a calcium channel blocker, has modest selectivity for T-type Ca2+ channels so that could be used in the treatment of sorts of cardiovascular disease...
Evenamide is a selective voltage-gated sodium and/or calcium channel modulator, including subtypes Nav1.3, Nav1.7, and Nav1.8. It may be potentia useful in pre...
Efonidipine hydrochloride monoethanolate
The hydrochloride monoethanolate salt form of Efonidipine which has been launched for hypertension and discontinued for cerebrovascular disorders.
Nicardipine is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders.
Gabapentin HCl is a GABA analogue.Originally it was developed to treat epilepsy, and is currently used to relieve neuropathic pain and restless leg syndrome.
UK-1745, an indole derivative, has been found to be a Calcium channel antagonist that was once studied in the treatment of arrhythmias as well as heart failure.
Etripamil, a benzoates derivative, has been found to be a calcium channel antagonist that could be used against hypertension and arrhythmic. It is currently und...
Efonidipine could be effective in the treatment of cardiovascular disease as a blocker of T-type and L-type calcium channels. It could also present as the hydro...
Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM.
Cinnarizine, with antiallergic and anti-vasoconstricting activity, is a calcium channel blocker to treat cerebral apoplexy, post-trauma cerebral symptoms, and c...
Ca2+ Channel Agonist 1
A Ca2+ Channel Agonist that selectively acting on N-type Ca2+ channel and also be found to restrain the cdk activity at some extent. IC50: 14.23 uM (EC50, Ca2+ ...
YS-201, also known as Diperdipine, is a dihydropyridine-type calcium channel antagonist potentially for the treatment of angina pectoris and hypertension.
S(-)-BAY K 8644
S(-)-BAY K 8644 is an activator of voltage-sensitive L-type calcium channels with positive inotropic, vasoconstrictive and behavioral effects in vivo. It is the...
Diltiazem is a nondihydropyridines (non-DHP) calcium channel blocker used in the treatment of hypertension, angina pectoris, and some types of arrhythmia as a p...
Manidipine 2HCl, a HCl salt form of Manidipine, is a calcium channel blocker with IC50 of 2.6 nM.