|Description||Gabapentin enacarbil (XP-13512) is a prodrug for the anticonvulsant and analgesic drug gabapentin.|
|Synonyms||Horizant; Regnite; XP-13512|
NNC 55-0396 dihydrochloride
NNC 55-0396 is a derivative of Mibefradil as a T-type calcium channel blocker (IC50=6.8 nM)
Osthole is a coumarin which is isolated from Cnidium monnieri (L.) Cusson. Osthole is a calcium channel modulator via inhibiting phosphodiesterases. It also reg...
Dantrolene Sodium, an inhibitor of calcium channel proteins that markedly suppresses the release of calcium previously sequestered by skeletal, but not cardiac,...
OPC 13463 is one of the metabolites of pranidipine. Pranidipine is a long acting calcium channel antagonist of the dihydropyridine group.
Tamolarizin is a calcium antagonist originated by Nippon Chemiphar. Tamolarizin can induce the increase of GABA in the cerebellum and medulla oblongata followin...
S(-)-BAY K 8644
S(-)-BAY K 8644 is an activator of voltage-sensitive L-type calcium channels with positive inotropic, vasoconstrictive and behavioral effects in vivo. It is the...
Penfluridol (Semap, Micefal, Longoperidol) is a highly potent, first generation diphenylbutylpiperidine antipsychotic. It was discovered at Janssen Pharmaceutic...
Nisoldipine is a calcium channel blocker, specific for L-type Cav1.2 with IC50 of 10 nM.
GAL-021 a novel intravenous BKCa-channel blocker potentially for the treatment of respiratory depression.
Mibefradil, a calcium channel blocker, has modest selectivity for T-type Ca2+ channels so that could be used in the treatment of sorts of cardiovascular disease...
Watanipidine, also called as AE 0047 or Calbren, is a calcium channel antagonist.
Zonisamide is the first agent of this chemical class to be developed as an antiepileptic drug blocks repetitive firing of voltagesensitive sodium channels and r...
Gabapentin is structurally similar to GABA and is reported in various research studies to increase GABA concentrations within the brain. Gabapentin is also note...
Flunarizine 2HCl is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM.
Azelnidipine is a dihydropyridine calcium channel blocker.
Nifedipine is a dihydropyridine calcium channel blocker that primarily blocks L-type calcium channels.Its main uses are as an antianginal (especially inPrinzmet...
This active molecular is an α2δ-1 ligand being developed for pain associated with diabetic peripheral neuropathy, fibromyalgia, and postherpetic neuralgia which...
This active molecular is a calcium channel antagonist with sodium channel stimulating property as a dihydropyridine. PD 122860 can increase left ventricular con...
CP-060 is a novel type of Ca(2+) antagonist possessing both Ca(2+) overload inhibition, with antioxidant and cardioprotective activities.
ABT-639, a new blocker of selective T-type Ca2+ channel blocker, has been found to have potential effect against neuropathic and nociceptive pain in studies. It...