G‑5555 - CAS 1648863-93-7
Catalog number:
1648863-93-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H25ClN6O3
Molecular Weight:
492.96
COA:
Inquire
Targets:
p21-activated Kinases (PAKs)
Description:
G‑5555, a pyridopyrimidine derivative, has been found to be a PAK1 inhibitor that could be significant in anticancer studies. Ki=3.7 nM.
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Purity:
98%
Appearance:
Powder
Synonyms:
G‑5555; G 5555; G5555; 8-(((2r,5r)-5-amino-1,3-dioxan-2-yl)methyl)-6-(2-chloro-4-(6-methylpyridin-2-yl)phenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one
Solubility:
DMSO: 10 mM.
Storage:
Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).
MSDS:
Inquire
Quality Standard:
In-house standard
Quantity:
Milligram-Grams
InChIKey:
ZBCMHWUFWQFPLV-UHFFFAOYSA-N
InChI:
InChI=1S/C25H25ClN6O3/c1-14-4-3-5-21(30-14)15-6-7-18(20(26)9-15)19-8-16-10-29-25(28-2)31-23(16)32(24(19)33)11-22-34-12-17(27)13-35-22/h3-10,17,22H,11-13,27H2,1-2H3,(H,28,29,31)
Canonical SMILES:
CC1=CC=CC(=N1)C2=CC(=C(C=C2)C3=CC4=CN=C(N=C4N(C3=O)CC5OCC(CO5)N)NC)Cl
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