Funapide - CAS 1259933-16-8
Catalog number:
1259933-16-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C22H14F3NO5
Molecular Weight:
429.35
COA:
Inquire
Targets:
Sodium Channel
Description:
Funapide is a Nav1.7 and Nav1.8 voltage-gated sodium channel inhibitor under the development by Xenon Pharmaceuticals and Teva Pharmaceutical Industries. It is applicated for the treatment of a variety of chronic painconditions, including osteoarthritis, neuropathic pain, postherpetic, neuralgia, erythromelalgia and dental pain. In July 2014, Funapide has reached phase IIb clinical trials.
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Purity:
98%
Appearance:
Powder
Synonyms:
UNII-A5595LHJ2L; A5595LHJ2L; XEN-401-S; TV-45070; (7S)-1'-[[5-(trifluoromethyl)furan-2-yl]methyl]spiro[6H-furo[2,3-f][1,3]benzodioxole-7,3'-indole]-2'-one
Solubility:
Soluble in DMSO
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
chronic painconditions
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
NEBUOXBYNAHKFV-NRFANRHFSA-N
InChI:
InChI=1S/C22H14F3NO5/c23-22(24,25)19-6-5-12(31-19)9-26-15-4-2-1-3-13(15)21(20(26)27)10-28-16-8-18-17(7-14(16)21)29-11-30-18/h1-8H,9-11H2/t21-/m0/s1
Canonical SMILES:
C1C2(C3=CC=CC=C3N(C2=O)CC4=CC=C(O4)C(F)(F)F)C5=CC6=C(C=C5O1)OCO6
Current Developer:
Teva Pharmaceutical Industries; Xenon Pharmaceuticals
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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