|Description||Thesuccinate salt form of Frovatriptan, a carbazole derivative, has been found to be a 5-HT receptor agonist that could be used as an antimigraine agent.|
|Synonyms||Frovatriptan succinate; (3R)-2,3,4,9-Tetrahydro-3-(methylamino)-1H-carbazole-6-carboxamide butanedioate;1H-Carbazole-6-carboxamide, 2,3,4,9-tetrahydro-3-(methylamino)-, (3R)-, butanedioate (1:1);Sb-209509ax;Vml 251|
|Storage||Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).|
|Quality Standard||In-house standard|
BMY 14802 hydrochloride
BMY 14802 hydrochloride is a potent sigma receptor antagonist (IC50 = 112 nM) with weak affinity for 5-HT1A and α1 receptors. BMY 14802 is potentially used as a...
The hydrochloride salt form of Ziprasidone which is an antagonism of both serotonin and dopamine receptor and could be effective against schizophrenia.
LY310762 has a higher affinity for the guinea pig 5-HT1D receptor than for the 5-HT1B receptor. LY310762 potentiates the potassium-induced [3H]5-HT outflow from...
SB 206553 hydrochloride
SB 206553 hydrochloride is a potent and selective 5-HT2B/5-HT2C receptor antagonist (rat 5-HT2B pA2 = 8.89, human 5-HT2C pKi = 7.92) with > 80-fold selectivity ...
BRL 15572 hydrochloride
BRL 15572 hydrochloride is a selective h5-HT1D antagonist with 60-fold selectivity over h5-HT1B.
WY 45233 succinate
WY 45233 succinate is an inhibitor of serotonin and noradrenalin reuptake (SNRI) used in the treatment of major depressive disorder (MDD). WY 45233 succinate in...
Naratriptan, a 5-HT1B/1D receptor agonist, could be used in the treatment of migraine.
LY 272015 hydrochloride
LY 272015 hydrochloride is a selective 5-HT2B receptor antagonist.
Alverine Citrate is a highly potent competitive CXCR4 antagonist with EC50 of 0.3 nM.
LY 344864 is a brain penetrant, full agonist that specifically targets 5-HT1F receptor (pKi = 8.2) with > 80-fold selectivity over other serotonin receptors (Ki...
WAY-100635 maleate is a potent and selective 5-hydroxytryptamine1A antagonist for 5-HT ( IC50= 0.95 ± 0.12 nM ), and also exhibits agonist activity at dopamine ...
Risperidone is a serotonin 5-HT2 receptor blocker and a potent dopamine D2 receptor antagonist.
GR 46611 is a 5-HT1D receptor agonist that may be beneficial for the treatment of migraine. 5-HT1D acts on the central nervous system.
SB-242084 HCl salt
SB-242084 is a psychoactive drug and research chemical which acts as a selective antagonist for the 5HT2C receptor. It can increase the effectiveness of the sel...
SB 204741 is a potent and selective 5-HT2B receptor antagonist (pA2 = 7.95) with ≥ 135-fold selectivity over 5-HT2C (pKi = 5.82), 5-HT2A (pKi < 5.2), 5-HT1A, 1D...
RO 04-6790 hydrochloride
RO 04-6790 hydrochloride is a potent and selective serotonin 5-HT6 receptor antagonist.
MDL 100907 is a selective 5-HT2A receptor antagonist with Ki value of 0.36 nM. It shows antipsychotic activity, attenuates impulsivity, and augments antidepress...
CP 93129 dihydrochloride
The hydrochloride salt form of CP 93129, which is a 5HT1B agonist and exhibits activities in decreasing body weight as well as reducing food intake in rats.
Isoclozapine is a 2-Cl analogue of clozapine as a typical antipsychotic.
Elzasonan citrate is a selective 5-hydroxytryptamine 1B receptor antagonist for treat patients with major depressive disorder and obsessive compulsive disorder.