Freselestat - CAS 208848-19-5
Catalog number: B0084-101783
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C23H28N6O4
Molecular Weight:
452.51
COA:
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Targets:
Elastase
Description:
Freselestat is a high affinity and selective human neutrophil elastase 1 (HNE1) inhibitor (Ki = 12 nM) with >100-fold less activity at other related proteases including trypsin, pancreatic elastase, collagenase and murine macrophage elastase. Freselestat can be used as treatment for neutrophil-predominant inflammatory lung diseases.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-101783 10 mg $299 In stock
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Purity:
95%
Appearance:
Solid powder
Synonyms:
2-(5-amino-6-oxo-2-phenylpyrimidin-1-yl)-N-[1-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-3-methyl-1-oxobutan-2-yl]acetamide; ONO 6818; ONO-6818
MSDS:
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Quantity:
Data not available, please inquire.
InChIKey:
YSIHYROEMJSOAS-UHFFFAOYSA-N
InChI:
1S/C23H28N6O4/c1-13(2)17(18(31)20-27-28-22(33-20)23(3,4)5)26-16(30)12-29-19(14-9-7-6-8-10-14)25-11-15(24)21(29)32/h6-11,13,17H,12,24H2,1-5H3,(H,26,30)
Canonical SMILES:
CC(C)C(C(=O)C1=NN=C(O1)C(C)(C)C)NC(=O)CN2C(=NC=C(C2=O)N)C3=CC=CC=C3
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