FRAX1036 - CAS 1432908-05-8
Catalog number:
1432908-05-8
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C28H32ClN7O
Molecular Weight:
518.06
COA:
Inquire
Targets:
p21-activated Kinases (PAKs)
Description:
FRAX1036 is a highly selective PAK1 inhibitor that remarkably altered signaling to cytoskeletal-associated proteins. In vitro and in vivo tests with FRAX-1036 have shown that the small-molecule inhibitor can both deter proliferation in ovarian cancer cell
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Appearance:
White to off-white Solid
Synonyms:
6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[2-(1-methylpiperidin-4-yl)ethylamino]pyrido[2,3-d]pyrimidin-7-one FRAX1036 SCHEMBL14928919 CS-5585 HY-19538
Solubility:
Soluble in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -47℃ for long term (months to years).
MSDS:
Inquire
Shelf Life:
2 years
Quantity:
Grams-Kilos
Boiling Point:
669.8±65.0 °C | Condition: Press: 760 Torr
Density:
1Ϋ+-.0.06 g/cm3
InChIKey:
RYCBSFIKWACFBY-UHFFFAOYSA-N
InChI:
1S/C28H32ClN7O/c1-4-36-26-21(16-32-28(34-26)31-10-7-19-8-11-35(3)12-9-19)13-23(27(36)37)22-6-5-20(14-24(22)29)25-17-30-15-18(2)33-25/h5-6,13-17,19H,4,7-12H2,1-3H3,(H,31,32,34)
Canonical SMILES:
CCN1C2=NC(=NC=C2C=C(C1=O)C3=C(C=C(C=C3)C4=CN=CC(=N4)C)Cl)NCCC5CCN(CC5)C
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