|Description||FR-193262 is a designed prostacyclin mimetic without PG skeleton which exhibits potent PGI2 agonistic activity with good selectivity for IP receptor and bioavailability.|
|Appearance||White to off-white crystalline solid|
|Synonyms||sodium;2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetate; FR-193262; 187992-22-9(FR-193262); 314289-63-9 (FR-193262 Free Base)|
Ginkgetin is a natural biflavonoid isolated from leaves of Ginkgo biloba L. According to reports, it has anti-inflammatory and anti-cancer effects.
Angiotensin 1 Human
Angiotensin 1 (Human), an endogenous peptide substrate for angiotensin converting enzyme (ACE), is precursor to the vasoconstrictor peptide angiotensin II.
Glisoxepide, a second-generation sulfonylurea, exerts greater binding affinity than the first-generation compounds. With antihyperglycemic activity, Glisoxepide...
Nonoxinol 9, also called as Advantage S or Delfen Cream, belongs to the nonoxynol family of nonionic surfactants.
TUG-891 is a selective free fatty acid receptor 4 (FFA4/GPR120)agonist. pEC50 values are 7.36 for human and 7.77 for mouse GPR120. TUG-891 also activates GPR40 ...
SEW 2871 is a potent, cell-permeable and selective sphingosine-1-phosphate type 1 receptor agonist (EC50= 13 nM). SEW 2871 suppresses the immune response by dec...
CP-640186 is a potent inhibitor of mammalian ACCs and can reduce body weight and improve insulin sensitivity in test animals. It has recently been shown to be a...
CI-750 is a novel antidiarrheal agent.
Solasodine is a neuroprotective antioxidant glycoalkaloid of Solanum species. Solasodine increases superoxide dismutase (SOD), catalase (CAT),and glutathione (G...
Nedocromil is an inhaled anti-inflammatory agent for the preventive management of asthma.
Cinepazide is a vasodilator. Cinepazide (30 mg/kg, i.v.) potentiated the vertebral vasodilator response of dogs to intravertebral adenosine and cyclic AMP, Intr...
J 147, under the IUPAC name N-(2,4-dimethylphenyl)-2,2,2-trifluoro-N-[(E)-(3-methoxyphenyl)methylideneamino]acetamide, a phenyl hydrazide compound that has been...
Hoechst 33342 trihydrochloride
Hoechst 33342 trihydrochloride is a cell-permeable, benzimidazole dye that stains DNA by binding to the minor groove of adenine and thymine-rich sequences. It e...
CP 81282 shows human renin and endothiapepsin inhibitory efficacy, but no detailed data has been published yet.
Ozanimod (RPC1063) is a selective oral S1P Receptor 1 modulator. Phase 3.
Macranthoidin B, a triterpenoid saponin compound, could be isolated from flowerbuds of Lonicera and has been found to have potential effect against inflammation...
Napabucasin is an orally-administered small molecule which can block cancer stem cell (CSC) self-renewal and induces cell death in CSCs as well as non-stem canc...
Ajmaline is an alkaloid which could extracted from Rauwolfia serpentina. It is an antiarrhythmic agent, acting through changing the shreshold and the shape of c...
Cyclocytidine is the prodrug of cytarabine, which is a pyrimidine nucleoside analog that inhibits the DNA synthesis and used mainly in the treatment of leukemia...
Galangin is a flavonoid naturally found in herbs acts as an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.