FR 122047 hydrochloride - CAS 130717-51-0
Catalog number:
130717-51-0
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C23H25N3O3S.HCl
Molecular Weight:
459.99
COA:
Inquire
Targets:
COX
Description:
FR-122047 is a selective cyclooxygenase-1 (COX-1) inhibitor with IC50 values is 0.028μM for COX-1 and 65 μM for COX-2. FR-122047 displays 2300 fold greater selectivity towards inhibition of COX-1 over COX-2. It shows analgesic, anti-platelet and anti-inflammatory properties. No development was reported for the treatment of Pain, Rheumatoid arthritis and Thrombosis.
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Purity:
>98 %
Appearance:
Pale yellow solid
Synonyms:
FR 122047 hydrochloride;1-[[4,5-bis-(4-Methoxyphenyl)-2-thiazolyl]carbonyl]-4-methylpiperazine hydrochloride
Solubility:
water to 10 mM 1eq. HCl to 5 mM DMSO to 100 mM ethanol to 25 mM
Storage:
-20°C Freezer
MSDS:
Inquire
Application:
Pain; Rheumatoid arthritis; Thrombosis
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
InChIKey:
YWMAVHIKOAOSFM-UHFFFAOYSA-N
InChI:
1S/C23H25N3O3S.ClH/c1-25-12-14-26(15-13-25)23(27)22-24-20(16-4-8-18(28-2)9-5-16)21(30-22)17-6-10-19(29-3)11-7-17;/h4-11H,12-15H2,1-3H3;1H
Canonical SMILES:
N1(CCN(CC1)C)C(=O)c1sc(c(n1)c1ccc(cc1)OC)c1ccc(cc1)OC.Cl
Current Developer:
Originator Fujisawa
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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