Fostriecin sodium salt - CAS 87860-39-7
Category: Inhibitor
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Molecular Formula:
C19H26O9PNa
Molecular Weight:
452.37
COA:
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Targets:
Others
Description:
Fostriecin sodium salt is a protein phosphatase types 2A (PP2A) and 4 (PP4) inhibitor (IC50 = 1.5 nM and 3 nM, respectively). It also has an inhibitory effect on topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM). Fostriecin is found in Streptomyces pulveraceous.
Brife Description:
PP2A and PP4 inhibitor
Purity:
≥98% by HPLC
Synonyms:
Fostriecin Sodium; Antibiotic CI 920 sodium salt; (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt
MSDS:
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InChIKey:
XBUIKNRVGYFSHL-BVOMIPGGSA-M
InChI:
InChI=1S/C19H27O9P.Na/c1-19(23,12-11-16-9-7-10-18(22)27-16)17(28-29(24,25)26)14-15(21)8-5-3-2-4-6-13-20;/h2-8,10-12,15-17,20-21,23H,9,13-14H2,1H3,(H2,24,25,26);/q;+1/p-1/b3-2+,6-4+,8-5+,12-11+;
Canonical SMILES:
CC(C=CC1CC=CC(=O)O1)(C(CC(C=CC=CC=CCO)O)OP(=O)(O)[O-])O.[Na+]
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CAS 87860-39-7 Fostriecin sodium salt

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