Foresaconitine - CAS 73870-35-6
Catalog number:
73870-35-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C35H49NO9
Molecular Weight:
627.76
COA:
Inquire
Targets:
Others
Description:
Foresaconitine is a norditerpenoid alkaloid isolated from the processed tubers of Aconitum carmichaeli.
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Purity:
>98%
Synonyms:
Vilmorrianine C
MSDS:
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1.Norditerpenoid alkaloids from the processed tubers of Aconitum carmichaeli.
Shim SH1, Kim JS, Kang SS. Chem Pharm Bull (Tokyo). 2003 Aug;51(8):999-1002.
Four new and five known norditerpenoid alkaloids were isolated from the processed tubers of Aconitum carmichaeli. The new alkaloids are 14-O-cinnamoylneoline (3), 14-O-anisoylneoline (4) 14-O-veratroylneoline (5), and lipo-14-O-anisoylbikhaconine (8). The known alkaloids are neoline (1), 14-O-acetylneoline (2), foresaconitine (6), crassicauline A (7), and lipohypaconitine (9). Alkaloids 2, 6, and 7 were isolated from this plant for the first time. The structures of the new alkaloids were established by spectroscopic and chemical methods.
2.Simultaneous determination of three aconitum alkaloids in urine by LC-MS-MS.
ZhaohongWang1, Wang Z, Wen J, He Y. J Pharm Biomed Anal. 2007 Sep 21;45(1):145-8. Epub 2007 Apr 20.
A sensitive method has been developed for the identification and quantification of the toxic alkaloids yunaconitine, crassicauline A, and foresaconitine in urine specimens. After solid-phase extraction using Oasis MCX cartridges, the extracts were analyzed by LC-MS-MS. The limit of detection is 0.03 ng/mL urine for yunaconitine and 0.05 ng/mL urine for crassicauline A and foresaconitine; the limit of quantitation is 0.15 ng/mL urine for yunaconitine and 0.20 ng/mL urine for crassicauline A and foresaconitine. The method was employed in the analysis of the urine of a 55-year-old male who died after ingestion of herbal medicine powder made from the roots of aconite. Yunaconitine, crassicauline A and foresaconitine were identified in the urine. Crassicauline A and foresaconitine were thus identified in a biological specimen for the first time.
3.[Chemical constituents of Aconitum bulleyanum].
Yuan M1, Ma XX1, Yang SD1, Zhou ZH1, Yang ZY1. Zhong Yao Cai. 2013 Jun;36(6):938-40.
OBJECTIVE: To study the chemical constituents of chloroform fraction from Aconitum bulleyanum.
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CAS 73870-35-6 Foresaconitine

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