|Description||Dimetotiazine is a histamine H1 receptor antagonist. It is a phenothiazine drug used for the treatment of migraine.|
|Synonyms||Fonazine; Dimetotiazine; Dimethothiazine; Dimetiotazine; Banistyl; Dimethodin; fonazine mesylate; fonazine monomesylate ;Migristene; Promaquid;10-(2-(Dimethylamino)propyl)-N,N-dimethylphenothiazine-2-sulfonamide;7455-39-2(Dimetotiazine Mesilate)|
|Solubility||Soluble in DMSO|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
Ebrotidine(FI 3542), a competitive H2-receptor antagonist, has gastroprotective activity under the condition of gastric mucosal damage caused by some stress res...
JNJ 10181457 dihydrochloride
The hydrochloride salt form of JNJ 10181457, which has been found to be a histamine H3 receptor inhibitor and could be a brain penetrant.
Ranitidine is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in treatment of peptic ulcer disease and gastroesoph...
Proxyfan oxalate is a high affinity histamine H3 receptor ligand (pKi = 8.62), acting as a protean agonist with activity ranges from full agonist to inverse ago...
A 943931 is a potent and selective histamine H4 receptor antagonist.
Clemastine Fumarate (Clemastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM.
Immethridine dihydrobromide is the dihydrobromide salt of immethridine, which is a highly selective, potent and novel histamine H3 receptor agonist with pEC50 v...
GSK-239512 is a histamine H3 receptor antagonist. In Jun 2015, Phase-II for Schizophrenia in USA was discontinued. Phase II clinical trilas for the treatment of...
Epinastine is a second-generation antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. It is highly selective for ...
Diphenhydramine is a histamine H1 antagonist. t competitively inhibits the histamine-1 (H1) receptor, thereby alleviating the symptoms caused by endogenous hist...
Alimemazine is a phenothiazine derivative as a Histamine Receptor antagonist. It can be used as an antipruritic . It also acts as a sedative, hypnotic, and anti...
Loratadine is a histamine H1 receptor antagonist, used to treat allergies. It also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
Brompheniramine hydrogen maleate
Brompheniramine hydrogen maleate is a histamine H1 receptors antagonist.
Tiotidine is a potent histamine H2 receptor antagonist with negligible activity against H1- and H3- receptors.
ICI 162,846 is a potent histamine H2 receptor antagonist.
The hydrochloride salt form of Dimaprit, which has been found to be a histamine H2 receptor agonist.
Ebastine is a nonsedating type histamine H1-receptor antagonist.
VUF10460 is a specific non-imidazole histamine H4 receptor agonist (pKi= 7.46, 8.22 for rat H4 receptor and human H4 receptor respectively) with 50-fold selecti...
JNJ10181457 dihydrochloride is a selective non-imidazole brain penetrant histamine H3 receptor antagonist with pKi values of 8.15 and 8.93 for rat and human H3 ...
Mizolastine is a histamine H1-receptor antagonist with IC50 of 47 nM used in the treatment of hay fever (seasonal allergic rhinitis), hives and other allergic r...