|Description||Flupirtine is an agonist of Kv7 potassium (KCNQ) channels, doubles channel currents when applied at 10 µM.|
|Solubility||Soluble in DMSO|
|Storage||Store at -20 °C|
|Application||Non-opioid analgesic with muscle relaxant properties|
|Quality Standard||Enterprise standard|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.|
Amiodarone HCl is a sodium/potassium-ATPase inhibitor and an autophagy activator, used to treat various types of cardiac dysrhythmias.
ZM 260384, a benzoxazine derivative, has been found to be a potassium channel agonist that was once studied against hypertension and thrombus.
KRN4884, a synthesized 3-pyridine derivative, shows a long-lasting antihypertensive effect based on its potent potassium channel-opening action. The long-lastin...
ML213 is a selective activator of KCNQ2 (Kv7.2) and KCNQ4 (Kv7.4) with > 80-fold selectivity against other related K+ channels, and enhances Kv7.2 and Kv7.4 cha...
U89232, a cardioselective cyanoguanidine analog of cromakalim, appears to be a cardioselective KATP channel opener.
This active molecular is a selective renal outer medullary potassium channel (RMOK) inhibitor originated by Merck Sharp & Dohme for the treatment of hypertensio...
NS309 is a small- and intermediate- conductance Ca2+-activated K+ channels of SK and IK types whereas exhibits no activity at BK channels.
Dofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug
NS 1643 is human ether-a-go-go related gene (hERG) KV11.1 channel activator (EC50 = 10.5 μM)
ML-365 is a potent and novel selective small molecule inhibitor of TASK1 with IC50 of 4 nM(thallium influx fluorescent assay) and 16 nM(automated electrophysiol...
Amiodarone, an iodine-rich benzofuran derivative, as a vaughan-Williams Class III antiarrhythmic agent it is an ATP-sensitive potassium channel inhibitor (IC50=...
Carabersat, also called as SB 204269, an orally-effective anticonvulsant agent, is an ATP-sensitive potassium channel (K-ATP) opener with potential effect to t...
Minoxidil is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth.
AZD1305 is a potassium channel and sodium channel antagonist. It can inhibit rapidly the activating delayed-rectifier potassium current, L-type calcium current,...
Mitiglinide calcium hydrate
Mitiglinide calcium hydrate, a derivative of benzylsuccinic acid, is a highly selective KATP channel antagonist.
Flupirtine is an agonist of Kv7 potassium (KCNQ) channels, doubles channel currents when applied at 10 µM.
Dequalinium Chloride is a PKC inhibitor with IC50 of 7-18 μM, and also a selective blocker of apamin-sensitive K+ channels with IC50 of 1.1 μM.
BMS 191011 is a potent opener of the large-conductance, Ca2+-activated potassium (maxi-K) channel. It is neuroprotectant in two distinct animal models of stroke...
GYKI-16638 is Potassium channel and Sodium channel antagonist originated by Nonindustrial source. It is a novel antiarrhythmic agent.
Mitiglinide Calcium is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells.