|Description||Flupirtine is an agonist of Kv7 potassium (KCNQ) channels, doubles channel currents when applied at 10 µM.|
|Solubility||Soluble in DMSO|
|Storage||Store at -20 °C|
|Application||Non-opioid analgesic with muscle relaxant properties|
|Quality Standard||Enterprise standard|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.|
Flupirtine maleate is the salt form of Flupirtine, which is a centrally acting non-opioid analgesia, is a selective neuronal potassium channel opener that also ...
Mitiglinide calcium hydrate
Mitiglinide calcium hydrate, a derivative of benzylsuccinic acid, is a highly selective KATP channel antagonist.
Indapamide is a thiazide-like diuretic drug marketed by Servier, generally used in the treatment of hypertension, as well as decompensated heart failure. Combin...
BMS-191095 is an activators that has selective effects on mitochondrial ATP-sensitive potassium (mitoKATP) channels. in vitro: induces mitochondrial-depolarizat...
Azimilide, also called as Stedicor, a chlorophentlturany compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels. Phase III
Doxapram is a respiratory stimulant. Administered intravenously, doxapram stimulates an increase in tidal volume, and respiratory rate. Doxapram stimulates chem...
Amiodarone, an iodine-rich benzofuran derivative, as a vaughan-Williams Class III antiarrhythmic agent it is an ATP-sensitive potassium channel inhibitor (IC50=...
Celikalim is s ATP-sensitive potassium channel agonist originated by Wyeth. It increases K+ outward flux in dog and human airway smooth muscle. But clinical tri...
Halofantrine is a blocker of delayed rectifier potassium current via the inhibition of hERG channel used to treat malaria.
Tifenazoxide is a potent selective KATP channels opener with preference for Kir6.2/SUR1. Studies show that it inhibits glucose stimulated insulin release in vit...
Doxapram HCl inhibits TASK-1, TASK-3, TASK-1/TASK-3 heterodimeric channel function with EC50 of 410 nM, 37 μM, 9 μM, respectively.
S 9947 is a Kv1.5 or IKur channel blocker exhibiting a dual inhibitory effect against cloned (Kv1.5) and native (IKur) cardiac potassium current.
ML213 is a selective activator of KCNQ2 (Kv7.2) and KCNQ4 (Kv7.4) with > 80-fold selectivity against other related K+ channels, and enhances Kv7.2 and Kv7.4 cha...
AVE 0118 hydrochloride is a potassium channel blocker that has the potential for the treatment of sleep apnea syndrome. AVE 0118 functions without apparent effe...
RPR-260243 is a selective activator of the Human Ether-ago-go-Related Gene (hERG) (IC50 = 58 nM).
This active molecular is a Kv1.5 potassium channel inhibitor originated by Bristol-Myers Squibb. Treatment for paroxysmal atrial fibrillation is in Phase II cli...
Tolbutamide is an inhibitor of potassium channel, used for type II diabetes.
NS 1619, a benzimidazalone derivative, activates BKca channels in a number of tissues. However, the effect of NS 1619 was dependent upon the presence of Ca 2+ i...
Naminidil is an ATP-Sensitive Potassium Channel Vasodilator used for the treatment of Alopecia.
Gliclazide is a whole-cell beta-cell ATP-sensitive potassium currents blocker with an IC50 of 184 nM.