|Description||Flupirtine is an agonist of Kv7 potassium (KCNQ) channels, doubles channel currents when applied at 10 µM.|
|Solubility||Soluble in DMSO|
|Storage||Store at -20 °C|
|Application||Non-opioid analgesic with muscle relaxant properties|
|Quality Standard||Enterprise standard|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly.|
(±)-BMS 204352 is a potassium channel opener that can be used in the study of buspirone metabolites for treating movement disorders.
BeKm 1 is a potent and selective KV11.1 (hERG) channel blocker.
Doxapram is a respiratory stimulant. Administered intravenously, doxapram stimulates an increase in tidal volume, and respiratory rate. Doxapram stimulates chem...
(-)-[3R,4S]-Chromanol 293B is one of the chromanols, which inhibits cAMP-mediated Cl- secretion in colon crypts by a blockade of a cAMP-activated K+ conductance...
BDS I is a reversible Kv3.4 potassium channel blocker (IC50 = 47 nM) and Nav1.7 channel agonist. BDS I potentiates TTX-sensitive sodium currents in rat small do...
NS 3623 is a KV11.1 (hERG) and KV4.3 channel activator. It can activate the IKr and Ito currents and display antiarrhythmic activity.
AM 92016 hydrochloride
The hydrochloride salt form of AM 92016, which has been found to be a specific blocker of the time dependent delayed rectifier potassium current and probably be...
QAQ, a photoisomerizable molecule, is a photoswitchable Nav, Cav and Kv channel blocker, blocking channels in the trans form. It switches conformation from cis ...
GW 542573X is an activator of small-conductance Ca2+-activated K+ channels (KCa2) with selectivity for KCa2.1 (EC50 = 8.2 μM in HEK293 cells expressing hKCa2.1)...
This active molecular is a Kv1.5 potassium channel inhibitor originated by Bristol-Myers Squibb. Treatment for paroxysmal atrial fibrillation is in Phase II cli...
ICA-069673 is an orally active, potent and selective KCNQ2/Q3 potassium channel activator (IC50= 0.69 μM) with 20-fold selectivity for KV7.2/KV7.3 over KV7.3/KV...
Y-27152 is a prodrug of the Kir6 (KATP) channel opener Y-26763. It was demonstrated ability to produce long-lasting antihypertensive effects in vivo, with minim...
AZD0837 is an oral direct thrombin inhibitor currently in clinical development for the prevention of stroke and systemic embolic events in patients with atrial ...
BMS 191011 is a potent opener of the large-conductance, Ca2+-activated potassium (maxi-K) channel. It is neuroprotectant in two distinct animal models of stroke...
HLei-Dab 7 is a calcium-activated potassium channel blocker.
Flupirtine is an agonist of Kv7 potassium (KCNQ) channels, doubles channel currents when applied at 10 µM.
Pipemidic acid is a synthetic quinolone antibiotic agent as a ATP-sensitive K+ channel blocker.
Minoxidil is a vasodilator medication known for its ability to slow or stop hair loss and promote hair regrowth.
Glyburide (Glibenclamide) is an anti-diabetic compound in a class of medications known as sulfonylureas, closely related to sulfa agents.
Tertiapin LQ is a Kir1.1 channel blocker with >250-fold selectivity for Kir1.1 (Kd = 1.1, 274 and 361 nM for Kir1.1, Kir3.1/3.2 and Kir3.1/3.4, respectively). T...