|Description||Flunarizine is a selective calcium entry blocker, which has calmodulin binding properties and histamine H1 blocking activity. It may help to reduce the severity and duration of attacks of paralysis and is effective in rapid onset dystonia-parkinsonism. It is effective in the prophylaxis of migraine, vascular disease, occlusive peripheral, vertigo of central and peripheral origin. It is used as an adjuvant in the therapy of epilepsy. It has been shown to significantly reduce headache frequency and severity in both adults and children. It was discovered at Janssen Pharmaceutica in 1968. It has been listed.|
|Synonyms||Sibelium;Flunarizinum;Flunarizina;(E)-1-[Bis-(p-fluorophenyl)methyl]-4-cinnamylpiperazine;1-[Bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propenyl]piperazine;Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)-, (E)-|
|Solubility||Soluble in DMSO, not in water|
|Application||Flunarizine is effective in the prophylaxis of migraine, vascular disease, occlusive peripheral, vertigo of central and peripheral origin. It is used as an adjuvant in the therapy of epilepsy.|
|Quality Standard||In-house standard|
|Quantity||Kilograms to Tons|
|Boiling Point||511.3±50.0 °C | Condition: Press: 760 Torr|
|Density||1.170±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr|
|Current Developer||Flunarizine was discovered at Janssen Pharmaceutica in 1968. It has been listed.|
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