|Description||Flibanserin, a benzimidazole derivative, has been found to be a Serotonin 1A/2A receptor agonist that was once studied as antidepressant as well as anxiolytic agent and could be used against female sexual dysfunction.|
|Storage||Store in a cool and dry place and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).|
|Quality Standard||In-house standard|
(R)-(-)-LY 426965 dihydrochloride
(R)-(-)-LY 426965 dihydrochloride is a selective 5-HT1A antagonist that is less active than its opposite (S)-(+)-enantiomer LY 426965.
GMC 3-15 is a potent and selective 5-HT1B/1D antagonist.
BMS 181101, an indole derivative, has been found to be a 5-HT receptor agonist that could be probably effective against depression and also restrain serotonin r...
The (-)-enantiomer of Azasetron hydrochloride, which is a selective 5-HT3 antagonist.
Isoclozapine is a 2-Cl analogue of clozapine as a typical antipsychotic.
Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent.oxapine is a typical antipsych...
GMC 1-169 is an atypical antipsychotic devoid of muscarinic activity.
S 14506 is a potent and selective 5-HT1A agonist.
LY-293284 is a Serotonin 1A receptor agonist developed by Eli Lilly. It is a selective 5-HT1A receptor full agonist. LY-293284 is far more selective for 5-HT1A ...
Risperidone is a serotonin 5-HT2 receptor blocker and a potent dopamine D2 receptor antagonist.
SB-269970 is a selective 5-HT7 receptor antagonist (pKi of 8.3) with >50-fold selectivity against other receptors, on amphetamine and ketamine-induced hyperacti...
Zatosetron has been identified as a potent, orally available, long-acting, selective 5HT3 receptor antagonist, which is potentially useful in the treatment of c...
The citrate salt form of tandospirone, a partial 5HT1A receptors agonist, could be effective as an antianxiety and antidepressant agent.
Tertatolol, a benzothiopyran derivative, is a potent dual antagonist of beta-adrenoceptor and 5-HT receptor, with antihypertensive effect.
Mosapride, a selective agonist of 5-HT4 receptor, could be used as a astroprokinetic agent. It is also found to be a 5-HT3 receptor antagonist.
PRX 08066, a selective 5-hydroxytryptamine receptor 2B(5-HT2BR) antagonist, causes selective vasodilation of pulmonary arteries. Its IC50 value is 3.4 nM. It ca...
Granisetron is an antagonist of serptpmom 5-HT3 receptor and could be used to relieve the nausea and vomiting symptom after receving chemotherapy by decreasing ...
A 5-HT1A receptor partial agonist that is less active compared to R-(+)-8-hydroxy-DPAT.
Aripiprazole lauroxil is a Dopamine D2 receptor agonist, Serotonin 1A receptor agonist and ISerotonin 2A receptor antagonist under the development of Alkermes p...
Naratriptan, a 5-HT1B/1D receptor agonist, could be used in the treatment of migraine.