FLI-06 - CAS 313967-18-9
Catalog number: 313967-18-9
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H30N2O5
Molecular Weight:
438.22
COA:
Inquire
Targets:
Amyloid-β | Notch
Description:
FLI-06 , a Notch inhibitor that disrupts Notch trafficking and processing, disrupts the Golgi by mechanisms different from BFA or GCA. It Reduces amyloid β secretion.
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Brife Description:
Inhibits Notch signaling (EC50 = 2.3 μM); Reduces amyloid β secretion
Appearance:
White solid powder
Synonyms:
cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,6,8-tetrahydroquinoline-3-carboxylate; FLI-06; 313967-18-9; cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate; STK368879; AC1MIXAW; BAS 00380830; Oprea1_143746; Oprea1_499413; FLI 06; SCHEMBL15536952; AOB2707; SYN5099; 2412AH; AKOS000650664; AKOS021985195; CS-2407; MCULE-5112819342; BC600549; HY-15860; ST50001800; S7399,313967-18-9; 4-(4-Nitrophenyl)-5-oxo-2,7,7-trimethyl-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid cyclohexyl ester; cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,6,7,8-pentahydroquinoli ne-3-carboxylate; FLI 06|Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate;
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -43℃ for long term (months to years).
MSDS:
Inquire
Density:
1.25±0.1 g/cm3
InChIKey:
SWWVFYHSSOWZMF-UHFFFAOYSA-N
InChI:
1S/C25H30N2O5/c1-15-21(24(29)32-18-7-5-4-6-8-18)22(16-9-11-17(12-10-16)27(30)31)23-19(26-15)13-25(2,3)14-20(23)28/h9-12,18,22,26H,4-8,13-14H2,1-3H3
Canonical SMILES:
CC1=C(C(C2=C(N1)CC(CC2=O)(C)C)C3=CC=C(C=C3)[N+](=O)[O-])C(=O)OC4CCCCC4
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CAS 313967-18-9 FLI-06

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