|Targets||Amyloid-β | Notch|
|Description||FLI-06 , a Notch inhibitor that disrupts Notch trafficking and processing, disrupts the Golgi by mechanisms different from BFA or GCA. It Reduces amyloid β secretion.|
|Brife Description||Inhibits Notch signaling (EC50 = 2.3 μM); Reduces amyloid β secretion|
|Appearance||White solid powder|
|Synonyms||cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,6,8-tetrahydroquinoline-3-carboxylate; FLI-06; 313967-18-9; cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate; STK368879; AC1MIXAW; BAS 00380830; Oprea1_143746; Oprea1_499413; FLI 06; SCHEMBL15536952; AOB2707; SYN5099; 2412AH; AKOS000650664; AKOS021985195; CS-2407; MCULE-5112819342; BC600549; HY-15860; ST50001800; S7399,313967-18-9; 4-(4-Nitrophenyl)-5-oxo-2,7,7-trimethyl-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid cyclohexyl ester; cyclohexyl 2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-1,4,6,7,8-pentahydroquinoli ne-3-carboxylate; FLI 06|Cyclohexyl 1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-4-(4-nitrophenyl)-5-oxo-3-quinolinecarboxylate;|
|Solubility||Soluble to 100 mM in DMSO and to 20 mM in ethanol|
|Storage||Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -43℃ for long term (months to years).|
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