|Description||High affinity aryl hydrocarbon receptor (AhR) agonist (Kd = 70 p M). Proposed to be an endogenous AhR ligand. Induces transient expression of cytochrome P450-1A1 (CYP1A1) in vitro.|
P7C3-OMe, also known as (R)-P7C3-OMe, is a methoxy derivative of parent compound P7C3, an aminopropyl carbazole that exhibits antidepressant and neuroprotective...
CBR 5884 is a 3-Phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50 = 33 μM), does not affect other NAD+-dependent dehydrogenases.
MKC-231 (10(-10)-10(-6) moll) significantly increased high affinity choline uptake (HACU) when it was incubated with the hippocampal synaptosomes of ethylcholin...
Cyclo(RADfK) is a selective α(v)β(3) integrin ligand. It has been used for research, therapy, and diagnosis of neoangiogenesis. It is also used as a negative co...
Tiludronic acid disodium salt
The disodium salt form of Tiludronic acid which has been found to be a biphosphonate bone resorption inhibitor and could be used against osteitis deformans.
A natural furanocoumarin extract from lemon and bergamot acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme
Octocrylene is an organic compound used as an ingredient in sunscreens and cosmetics.
Bindarit treatment inhibits the release of MCP-1 from IL-1 stimulated osteoblast cell line Saos-2.
Ufenamate is a topical analgesic.
Eculizumab is a recombinant human IgG2/4κ monoclonal antibody used for the treatment of paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic ...
Pamidronate disodium pentahydrate
Pamidronate disodium pentahydrate is a nitrogen-containing bisphosphonate, used to prevent osteoporosis.
Mice treated with vehicle showed significantly enlarged tumors, whereas mice treated with YL-109 showed attenuated tumor growth using MCF-7 cells. Interestingly...
Acetylaconitine is a diterpenoid alkaloid isolated from the roots of Aconitum kusnezoffii Reichb. It is used in analgesia in rats for the treatment of chronic p...
Benzoylhypacoitine is extracted from the roots of Aconitum carmichaeli Debx. It might be the principal active components which affect mitochondrial growth by Fu...
Caftaric acid is a natural productwhich was reported as an inhibitor of the protein-protein interactions mediated by the Src-family kinases.
Peptide5 is a mimetic peptide of Connexin 43 (Cx43), which is the most ubiquitously expressed type of Cx in the skin. It reduces swelling, astrogliosis, neuroin...
Metaxalone is a muscle relaxant. The mechanism of action of metaxalone in humans is not fully understood. It was suggested that it acts through general central ...
Eldacimibe is a Sterol O-acyltransferase inhibitor originated by Wyeth. No development was reported for Atherosclerosis and Hypercholesterolaemia in USA.
TAK-683 is an investigational peptide derivative of metastin under the development of Millennium. It is a KISS1R protein agonist. Phase I development for prosta...