|Targets||PPAR | Wnt|
|Description||FH535 sodium salt is a dual inhibitor of peroxisome proliferator-activated receptor (PPAR) and Wnt/β-catenin/TCF/LEF signaling. FH535 inhibits recruitment of the coactivators β-catenin and GRIP1. FH535 is selectively toxic to carcinomas expressing the Wnt/β-Catenin pathway, leading to the inhibition of proliferation and motility of multiple cancer cells.|
|Brife Description||dual inhibitor of PPAR and Wnt/β-catenin/TCF/LEF signaling|
|Related CAS||108409-83-2 (free base)|
|Synonyms||FH535 sodium salt; FH 535 sodium salt; FH-535 sodium salt; (2,5-dichlorophenyl)sulfonyl-(2-methyl-4-nitrophenyl)azanide sodium salt|
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