FH535 sodium salt
Category: Inhibitor
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Molecular Formula:
C13H9Cl2N2NaO4S
Molecular Weight:
383.18
COA:
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Targets:
PPAR | Wnt
Description:
FH535 sodium salt is a dual inhibitor of peroxisome proliferator-activated receptor (PPAR) and Wnt/β-catenin/TCF/LEF signaling. FH535 inhibits recruitment of the coactivators β-catenin and GRIP1. FH535 is selectively toxic to carcinomas expressing the Wnt/β-Catenin pathway, leading to the inhibition of proliferation and motility of multiple cancer cells.
Brife Description:
dual inhibitor of PPAR and Wnt/β-catenin/TCF/LEF signaling
Purity:
99%
Related CAS:
108409-83-2 (free base)
Synonyms:
FH535 sodium salt; FH 535 sodium salt; FH-535 sodium salt; (2,5-dichlorophenyl)sulfonyl-(2-methyl-4-nitrophenyl)azanide sodium salt
MSDS:
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InChIKey:
KUOWFVORCZBNQF-UHFFFAOYSA-N
InChI:
InChI=1S/C13H9Cl2N2O4S.Na/c1-8-6-10(17(18)19)3-5-12(8)16-22(20,21)13-7-9(14)2-4-11(13)15;/h2-7H,1H3;/q-1;+1
Canonical SMILES:
CC1=C(C=CC(=C1)[N+](=O)[O-])[N-]S(=O)(=O)C2=C(C=CC(=C2)Cl)Cl.[Na+]
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