FGF-401 - CAS 1708971-55-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H30N8O4
Molecular Weight:
506.56
COA:
Inquire
Targets:
FGFR
Description:
FGF-401 is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) (IC50= 1.9 nM) developed for the treatment of solid tumor.
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Brife Description:
An inhibitor of FGFR4
Synonyms:
N-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-7-formyl-6-[(4-methyl-2-oxopiperazin-1-yl)methyl]-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
Solubility:
DMSO: 6 mg/mL (Need Ultrasonic)
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
852.1±65.0 ℃ at 760 Torr
Density:
1.39±0.1 g/cm3
InChIKey:
BHKDKKZMPODMIQ-UHFFFAOYSA-N
InChI:
1S/C25H30N8O4/c1-31-7-8-32(23(35)15-31)14-18-10-17-4-3-6-33(24(17)29-21(18)16-34)25(36)30-22-11-20(27-5-9-37-2)19(12-26)13-28-22/h10-11,13,16H,3-9,14-15H2,1-2H3,(H2,27,28,30,36)
Canonical SMILES:
CN1CCN(C(=O)C1)CC2=C(N=C3C(=C2)CCCN3C(=O)NC4=NC=C(C(=C4)NCCOC)C#N)C=O
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Chemical Structure

CAS 1708971-55-4 FGF-401

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