|Description||Fesoterodine Fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist.|
Milameline is a non-selective muscarinic acetylcholine receptor partial agonist at all receptor subtypes (Ki values are 2.3, 2.4, 3.6, 3.8 and 4.3 μM for hM1, h...
Methscopolamine is a muscarinic acetylcholine receptor blocker.
GYKI-46903 is a Muscarinic M3 receptor and Serotonin 3 receptor antagonist. In displacement studies, the pIC50 values of GYKI-46903 against [3H]granisetron bind...
MK-7622 is a cholinesterase inhibitor under evaluation for the treatment of Alzheimer's disease. No studies have been published on this compound in the peer-rev...
Pyrithioxin, a pyridine thiol derivatives, could be used in the treatment of traumatic brain injury sequelae and some sorts of cerebral infarct patients with He...
VU 6008667 is a selective negative allosteric modulator (NAM) of M5 muscarinic acetylcholine receptor (mAChR) (IC50 values of 1.2 and 1.6 μM in human and rat M5...
Oxyphencyclimine is a muscarinic cholinergic receptor antagonist and trade name is called as Daricon. Now it is applicated for the treatment of peptic ulcers an...
Homatropine Bromide is an muscarinic AChR antagonist, inhibits endothelial and smooth muscle muscarinic receptors of WKY-E and SHR-E with IC50 of 162.5 nM and 1...
Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties.
CDD0102 is a selective M1 agonist which stimulated the secretion of APP from CHO-K1 cells expressing M1 receptors and penetrated into the brain following i.p. a...
AF-DX 116 has been found to be a selective mAChR M2 antagonist.
Irsogladine is a PDE4 inhibitor and muscarinic acetylcholine receptor binder. It inhibits bFGF-induced angiogenesis in wild-type, tPA-knockout, and uPA-knockout...
Atropine is is a naturally occurring tropane alkaloid extracted from deadly nightshade acts as a competitive muscarinic acetylcholine receptor antagonist.
VU 0255035 is a highly selective M1 muscarinic acetylcholine receptor antagonist (Ki = 14.87 nM) with 75-fold greater selectivity for the M1 orthosteric site ov...
pilocarpine nitrate is a non-selective muscarinic receptor agonist that can be used to treat glaucoma.
mAChR-IN-1 is a potent muscarinic cholinergic receptor(mAChR) antagonist with IC50 of 17 nM.
Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist that has anticholinergic properties and could block pilocarpine-induced lacrimation.
Scopolamine HBr is a competitive muscarinic acetylcholine receptor with an IC50 of 55.3 nM.
Cevimeline hydrochloride hemihydrate
Cevimeline is a muscarinic M1 and M3 receptor agonist. Cevimeline stimulates secretion by the salivary glands and is used to treat the symptoms of dry mouth. Ce...
PD 102807 is a selective mAChR M4 antagonist with IC50 values of 91, 6559, 3441, 95 and 7412 nM for human M4, M1, M2, M3, and M5 receptors respectively.