|Description||Fesoterodine Fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist.|
Otilonium Bromide is an antimuscarinic used as a spasmolytic agent.
Zamifenacin is a Muscarinic M3 receptor antagonist originated by Pfizer. pKi value is 8.52 for M3 receptor, 7.93 for M2 receptor, 7.90 for M1 receptor and 7.78 ...
Trospium chloride is a competitive muscarinic cholinergic receptor antagonist.
Hyoscyamine is an AChR inhibitor with IC50 of 7.5 nM.
Anisodamine is a alkaloid shown to be a weak antagonist of α1-adrenoceptors, blocking WB-4101 and clonidine by binding in brain membrane preparations.
Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (C...
VU 6008667 is a selective negative allosteric modulator (NAM) of M5 muscarinic acetylcholine receptor (mAChR) (IC50 values of 1.2 and 1.6 μM in human and rat M5...
Methscopolamine is a muscarinic acetylcholine receptor blocker.
Diphenidol HCl is a potent antagonist of muscarinic M2 and M3 receptor with pKb of 6.72 and 7.02, respectively, used in the treatment of vomiting and vertigo.
This active molecular is a muscarinic agonist agent.
Methacholine chloride, a synthetic choline ester, is pharmaceutical agent acting as a β2-adrenergic agonist used in the treatment of pulmonary and respiratory d...
Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM).
Milameline is a non-selective muscarinic acetylcholine receptor partial agonist at all receptor subtypes (Ki values are 2.3, 2.4, 3.6, 3.8 and 4.3 μM for hM1, h...
Atropine sulfate salt monohydrate
Atropine is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 2.5 nM.
Flavoxate is an anticholinergic with antimuscarinic effects. Its muscle relaxant properties may be due to a direct action on the smooth muscle rather than by an...
Dicycloverine, also known as dicyclomine, is an anticholinergic that blocks muscarinic receptors.
Espatropate is a Muscarinic receptor antagonist originated by Pfizer. It is a bronchodilator with antimuscarinic activity. No development was reported for the t...
Cevimeline hydrochloride hemihydrate
Cevimeline is a muscarinic M1 and M3 receptor agonist. Cevimeline stimulates secretion by the salivary glands and is used to treat the symptoms of dry mouth. Ce...
PF-06767832 is a cell permeable, potent and selective M1 muscarinic acetylcholine receptor Positive Allosteric Modulator (PAM).
Scopolamine is an anti-muscarinic and cholinolytic alkaloid that inhibits parasympathetic-cholinergic system. The central effects include hallucinations, disori...