Ferulic acid sodium - CAS 24276-84-4
Catalog number:
24276-84-4
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C10H9NaO4
Molecular Weight:
216.17
COA:
Inquire
Targets:
5-HT Receptor
Description:
Ferulic acid sodium is one of the most abundant phenolic acids ubiquitously existing in plants. Free ferulic acid is a good antioxidant since it forms a resonancestabilized phenoxy radical. Ferulic acid showed high scavenging activity for hydrogen peroxid
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Purity:
>98%
Appearance:
Solid powder
Synonyms:
sodium;(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate 4-hydroxy-3-methoxycinnamic acid 8,8'-diferulic acid ferulic acid ferulic acid, (E)-isomer ferulic acid, (Z)-isomer ferulic acid, monosodium salt sodium ferulate
Solubility:
Soluble to 15mg/mL in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -109℃ for long term (months to years).
MSDS:
Inquire
Quality Standard:
Enterprise Standard
Shelf Life:
2 years
Quantity:
Grams-Kilos
InChIKey:
NCTHNHPAQAVBEB-WGCWOXMQSA-M
InChI:
1S/C10H10O4.Na/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13;/h2-6,11H,1H3,(H,12,13);/q;+1/p-1/b5-3+;
Canonical SMILES:
COC1=C(C=CC(=C1)C=CC(=O)[O-])O.[Na+]
1.Biological activities, phenolic profiles and essential oil components of Tanacetum cilicicum (BOISS.) GRIERSON.
Gecibesler IH1, Kocak A2, Demirtas I3. Nat Prod Res. 2016 Apr 8:1-6. [Epub ahead of print]
Tanacetum species are consumed as tea in Turkey. We comparatively evaluated the phytochemical potentials and antioxidant activities of the essential oil and methanolic extracts of Tanacetum cilicicum. The chemical constitutes of T. cilicicum essential oil and antioxidant activity of this species was analysed by gas chromatography-mass spectrometry (GC-MS) method. Bicyclo (3,1,1) hept-2-en-4-ol (21.92%), camphor (15.56%) and 1,8-cineole (13.45%) which are oxygenated monoterpenes were found as the major constituents. Phenolic acids and flavonoids were quantificated by HPLC-UV. Catechin was found as the main component. The essential oils and methanolic extracts were evaluated by antioxidant activities. The leaves exhibited significant metal chelation activity with a value of 20.75 ± 4.63 μg/mL.
2.Species-specific hydroxycinnamic acid degradation and siderophore biosynthesis pathways are regulated in a coordinated manner in Agrobacterium fabrum.
Baude J1, Vial L2, Villard C3, Campillo T4, Lavire C2, Nesme X2, Hommais F5. Appl Environ Microbiol. 2016 Apr 8. pii: AEM.00419-16. [Epub ahead of print]
The rhizosphere-inhabitingAgrobacterium fabrum(genomospecies G8 of theAgrobacterium tumefaciensspecies complex) is known to degrade hydroxycinnamic acids (HCAs), especially ferulic orp-coumaric acid, via the novelA. fabrumHCA degradation pathway. Gene expression profiles ofA. fabrum-type strain C58 were investigated, in the presence of HCAs, using a C58-whole-genome oligoarray. Both ferulic andp-coumaric acids caused variations in the expression of more than 10 % of the C58 genes. Genes of theA. fabrumHCA degradation pathway, together with the genes involved in iron acquisition, were amongst the most highly induced in the presence of HCAs. Two operons encoding for the biosynthesis of a particular siderophore, as well as genes of theA. fabrumHCA degradation pathway, have been described as being specific to the species. We demonstrate here their coordinated expression, emphasizing the interdependence between iron concentration in the growth medium and the rate at which ferulic acid is degraded by cells.
3.Evaluation of capacity to detect ability to form biofilm in Candida parapsilosis sensu stricto strains by MALDI-TOF MS.
Mlynáriková K1, Šedo O2,3, Růžička F4,5, Zdráhal Z2,3, Holá V1,6, Mahelová M1. Folia Microbiol (Praha). 2016 Apr 11. [Epub ahead of print]
Matrix assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is, currently, used as a rapid and reliable tool in microbial diagnostics. The discriminatory power of the method extends its applicability also beyond species level. This study examined the possibility to use MALDI-TOF MS to differentiate between Candida parapsilosis sensu stricto biofilm-positive (n = 12) and biofilm-negative (n = 9) strains. The results indicated a grouping trend within MALDI-TOF mass spectra belonging to each of the tested groups. However, these trends were eclipsed by mass spectral variations resulting from limited repeatability of the method, making its application for the selected purpose impossible. Improvement in the discriminatory power of the method was not obtained neither by using different matrices (α-cyano-4-hydroxycinnamic acid, ferulic acid, 5-chloro-2-mercaptobenzothionazole) for MALDI-TOF MS analysis nor by testing different culture conditions (cultivation length, culture media).
4.Antibacterial Constituents of Hainan Morinda citrifolia (Noni) Leaves.
Zhang WM1, Wang W1, Zhang JJ2, Wang ZR2, Wang Y2, Hao WJ2, Huang WY3. J Food Sci. 2016 Apr 13. doi: 10.1111/1750-3841.13302. [Epub ahead of print]
Noni (Morinda citrifolia L.) is an edible and medicinal plant distributed in Hainan, China. The antibacterial activities of the extracts of water (WE), petroleum ether (PEE), ethyl acetate (EAE), chloroform (CE), and n-butanol (BE) were assayed by the disk diffusion method. The results showed that the extracts from Noni leaves possessed antibacterial effects against Bacillus subtilis, Escherichia coli, Proteus vulgaris, and Staphylococcus aureus. Among 5 different extracts, the BE produced the best antibacterial activity. The samples were first extracted by ethanol, and the primary compounds in the BE fraction of ethanol extract was further isolated and identified. Six phenolic compounds, including 5, 15-dimethylmorindol, ferulic acid, p-hydroxycinamic acid, methyl 4-hydroxybenzoate, methyl ferulate, and methyl 4-hydroxycinnamate, were identifiedby NMR. The results indicated that the phenolic compounds might significantly contribute to antibacterial activities of Noni leaves.
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CAS 24276-84-4 Ferulic acid sodium

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