Fenaclonum - CAS 306-20-7
Catalog number:
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
Molecular Weight:
Fenaclon is a pharmaceutical intermediate.
Publictions citing BOC Sciences Products
  • >> More
Solid powder
3-chloro-N-(2-phenylethyl)propanamide Fenaclon Phenacone Fenakon Fenaclonum 306-20-7 3-Chloro-N-phenethylpropionamide
Soluble in DMSO
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -70℃ for long term (months to years).
Shelf Life:
2 years
Boiling Point:
398.6±35.0 °C | Condition: Press: 760 Torr
Melting Point:
58.9-59.5 °C
1.119±0.06 g/cm3
Canonical SMILES:
1.Determination of Anticoagulant Rodenticides and α-Chloralose in Human Hair. Application to a Real Case.
Leporati M1, Salomone A2, Golè G3, Vincenti M4. J Anal Toxicol. 2016 Mar 16. pii: bkw019. [Epub ahead of print]
Anticoagulant rodenticides are the largest group of poisons used to kill harmful rodents. Their fundamental mode of action consists in the inhibition of the vitamin K epoxide reductase, which causes blood-clotting alteration, ultimately leading to hemorrhagic events as the cause of death. In this study, we developed an UHPLC-MS-MS for the simultaneous determination of 10 anticoagulant hydroxycoumarine rodenticides, plus α-chloralose in human hair, with the scope of detecting potential trace of chronological poison exposure in clinical and forensic cases. The method was fully validated and applied to a case of intentional poisoning perpetrated by administration of difenacoum and α-chloralose to a 97-year old woman, who was hospitalized because of severe symptoms, including drowsiness, convulsions, pallor and hematoma. Hair sample from the victim was segmentally analyzed. Difenacoum was detected in the proximal 3-cm hair segment at the concentration of 2.
2.Anticoagulant rodenticides in red-tailed hawks, Buteo jamaicensis, and great horned owls, Bubo virginianus, from New Jersey, USA, 2008-2010.
Stansley W1, Cummings M, Vudathala D, Murphy LA. Bull Environ Contam Toxicol. 2014 Jan;92(1):6-9. doi: 10.1007/s00128-013-1135-z. Epub 2013 Oct 25.
Liver samples from red-tailed hawks (Buteo jamaicensis) and great horned owls (Bubo virginianus) were analyzed for anticoagulant rodenticides. Residues of one or more second generation anticoagulant rodenticides (SGARs) were detected in 81 % of red-tailed hawks and 82 % of great horned owls. The most frequently detected SGAR was brodifacoum, which was detected in 76 % of red-tailed hawks and 73 % of great horned owls. Bromadiolone was detected in 20 % of red-tailed hawks and 27 % of great horned owls. Difenacoum was detected in one great horned owl. No other ARs were detected. There were no significant differences between species in the frequency of detection or concentration of brodifacoum or bromadiolone. There was a marginally significant difference (p = 0.0497) between total SGAR residues in red-tailed hawks (0.117 mg/kg) and great horned owls (0.070 mg/kg). There were no seasonal differences in the frequency of detection or concentration of brodifacoum in red-tailed hawks.
3.Interspecific and geographical differences in anticoagulant rodenticide residues of predatory wildlife from the Mediterranean region of Spain.
López-Perea JJ1, Camarero PR2, Molina-López RA3, Parpal L4, Obón E3, Solá J4, Mateo R2. Sci Total Environ. 2015 Apr 1;511:259-67. doi: 10.1016/j.scitotenv.2014.12.042. Epub 2014 Dec 26.
We studied the prevalence of anticoagulant rodenticides (ARs) in the liver of 344 individuals representing 11 species of predatory wildlife that were found dead in the Mediterranean region of Spain (Catalonia and Majorca Island). Six different ARs (brodifacoum, bromadiolone, difenacoum, flocoumafen, difethialone, warfarin) were found in the liver of 216 (62.8%) animals and >1 AR co-occurred in 119 individuals (34.6%). The occurrence of ARs was positively correlated with the human population density. Catalonia and Majorca showed similar prevalence of AR detection (64.4 and 60.4%, respectively), but a higher prevalence was found in the resident population of Eurasian scops owl (Otus scops) from Majorca (57.7%) compared to the migratory population from Catalonia (14.3%). Birds of prey had lower levels of bromadiolone than hedgehogs, whereas no difference was found for other ARs. The risk of SGAR poisoning in wild predators in NE Spain is believed to be elevated, because 23.
4.A validated LC-MS-MS method for simultaneous identification and quantitation of rodenticides in blood.
Bidny S1, Gago K2, David M2, Duong T2, Albertyn D2, Gunja N3. J Anal Toxicol. 2015 Apr;39(3):219-24. doi: 10.1093/jat/bku175. Epub 2015 Jan 16.
A rapid, highly sensitive and specific analytical method for the extraction, identification and quantification of nine rodenticides from whole blood has been developed and validated. Commercially available rodenticides in Australia include coumatetralyl, warfarin, brodifacoum, bromadiolone, difenacoum, flocoumafen, difethialone, diphacinone and chlorophacinone. A Waters ACQUITY UPLC TQD system operating in multiple reaction monitoring mode was used to conduct the analysis. Two different ionization techniques, ES+ and ES-, were examined to achieve optimal sensitivity and selectivity resulting in detection by MS-MS using electrospray ionization in positive mode for difenacoum and brodifacoum and in negative mode for all other analytes. All analytes were extracted from 200 µL of whole blood with ethylacetate and separated on a Waters ACQUITY UPLC BEH-C18 column using gradient elution. Ammonium acetate (10 mM, pH 7.5) and methanol were used as mobile phases with a total run time of 8 min.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Products

CAS 106791-40-6 Mivacurium

(CAS: 106791-40-6)

Mivacurium is a bisbenzylisoquinolinium based and a short-duration non-depolarizing neuromuscular-blocking drug or skeletal muscle relaxant. It binds competitiv...

(CAS: 1353625-73-6)

Presatovir is a viral fusion protein inhibitor originated by Gilead Sciences with EC50 value of 0.43 nM. GS-5806 can inhibit a broad range of respiratory syncyt...

CAS 105558-26-7 Ginsenoside Rh3

Ginsenoside Rh3
(CAS: 105558-26-7)

Ginsenoside Rh3 is isolated from red ginseng and metabolized from ginsenoside Rg5 and could be used as an anti-inflammatory agent.

CAS 102-76-1 Triacetin

(CAS: 102-76-1)

Triacetin, an non-ionic surfactant, could be widely used because of its characteristics like dispersion, emulsification and solubilization capacity. The FEMA nu...

CAS 13171-25-0 Trimetazidine dihydrochloride

Trimetazidine dihydrochloride
(CAS: 13171-25-0)

Trimetazidine dihydrochloride, a piperazine derivative, could reduce fatty acid β-oxidation and used as a coronary vasodilator.

CAS 173352-39-1 Afobazole hydrochloride

Afobazole hydrochloride
(CAS: 173352-39-1)

Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any ...

CB 966
(CAS: 128312-71-0)

CB 966 is a novel analogues of 1,25-dihydroxyvitamin D3 and it was found to significantly delay the rejection of allogeneic skin grafts in CBA (H-2k) recipient ...

CAS 18771-50-1 Tetrahydrouridine

(CAS: 18771-50-1)

Tetrahydrouridine, a derivative of Uridine, is a potent and reversible competitive inhibitor of cytidine deaminase (CDD) (Ki values = 54 and 240 nM for human an...

ENT 25642
(CAS: 1713-54-8)

ENT 25642, a sulfamide derivative, could have potential activities in sorts of biological studies.

CAS 137-08-6 Calcium D-Panthotenate

Calcium D-Panthotenate
(CAS: 137-08-6)

Calcium D-Panthotenate, also called vitamin B5 Calcium, is a water-soluble vitamin and an essential nutrient for many animals.

CAS 538-71-6 Domiphen Bromide

Domiphen Bromide
(CAS: 538-71-6)

Domiphen bromide is a quaternary ammonium antiseptic with actions as a cationic surfactant.

CAS 56-04-2 Methylthiouracil

(CAS: 56-04-2)

Methylthiouracil is an antithyroid preparation.The drug acts to decrease the formation of stored thyroid hormone, as thyroglobulin in the thyroid gland.

(CAS: 105116-61-8)

CP-69799 is an inhibitor of aspartate proteinases.

CAS 119637-67-1 Moguisteine

(CAS: 119637-67-1)

Moguisteine is a novel peripheral nonnarcotic antitussive agent that has proved to be as active as codeine in several experimental models of induced cough in gu...

CAS 1222780-33-7 TPPU

(CAS: 1222780-33-7)

TTPU is a soluble epoxide hydrolase inhibitor (sEHI) (IC50= 37, 2.8 nM and 3.7 nM for monkey, mouse and human sEH, respectively) with anti-inflammatory, anti-hy...

CAS 682741-29-3 HTS01037

(CAS: 682741-29-3)

HTS01037, a high-affinity ligand of adipocyte fatty acid binding protein (A-FABP/aP2) (Ki = 0.67 μM), and is a competitive antagonist of protein-protein interac...

CAS 3863-59-0 Hydrocortisone phosphate

Hydrocortisone phosphate
(CAS: 3863-59-0)

Hydrocortisone is a corticosteroid increases blood sugar through gluconeogenesis to suppress the immune system.

CAS 603148-36-3 Azeliragon

(CAS: 603148-36-3)

Azeliragon is a potent and orally active RAGE inhibitor as a potential treatment for patients with mild-to-moderate Alzheimer's disease (AD).

CAS 143943-72-0 Ro 41-​3290

Ro 41-​3290
(CAS: 143943-72-0)

Ro 41-​3290, a desethylated metabolite of Ro 41-3696, has shown to be also a partial agonist at the benzodiazepine receptor.

6β-Naltrexol Hydrochloride
(CAS: 55488-86-3)

6β-Naltrexol Hydrochloride is a neutral opioid antagonist, as a metabolite of Naltrexone, which is an opioid antagonist.

Chemical Structure

CAS 306-20-7 Fenaclonum

Quick Inquiry

Verification code

Featured Items