|Description||The hydrate of Felbamate which is an effective anticonvulsant agent. It was found to be clinically active for probably restraining the effectivity of NMDA.|
|Synonyms||MLS000758238; SMR000449307; MLS001401392; CHEMBL2130858; HY-B0184A|
|Solubility||10 mM in DMSO|
|Application||The hydrate of Felbamate which is an effective anticonvulsant agent.|
|Shelf Life||As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly|
Dioxadrol hydrochloride has been found to be an NMDA antagonist and is used as a dissociative anaesthetic drug. It produces similar effects to PCP in animals. I...
Radiprodil is a orally active and selective NMDA NR2B antagonist with a potential therapeutic agent in treatment of neuropathic pain and possibly other chronic ...
Ro 25-6981, structurally related to ifenprodil and with no affinity for the known binding sites of non-competitive antagonists such as phencyclidine or MK-801, ...
Orphenadrine Citrate is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.
Dextromethorphan hydrobromide hydrate
Dextromethorphan, a dextratrorotatory morphinan, is a non-competitive, low affinity NMDA receptor antagonist.
LY 257883, also known as PPPA, is a competitive NMDA receptor antagonist which displays moderate selectivity for NR2A-containing receptors. Ki values are 0.13μM...
CGP 43487 has been found to be a NMDA receptor antagonist and was once studied about its influenment of dopaminergic function as a supplement in the treatment o...
MDL 105519, a ligand selective for the glycine binding site of NMDA receptor, was shown that completely inhibited the binding of [3H]glycine to rat brain membra...
CGP 31358 is a compound that can bind to a site on the N-methyl-D-aspartate (NMDA) receptor which is coupled to both the transmitter recognition site and the ch...
ZL006 is a potent inhibitor of nNOS/PSD-95 interaction. And in mice subjected to mCao and reperfusion, pretreatment with Zl006 attenuated the ischemia-induced i...
CIQ is a derivative of tetrahydroisoquinoline acts as subunit-selective potentiator of NMDA receptors containing the NR2C (EC50=2.7 μM) or NR2D (EC50=2.8 μM) su...
(-)-MK 801 Maleate
MK-801 is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes.
IC87201, an efficient inhibitor of PSD95-nNOS protein-protein interactions, was found by screening and shown to disrupt the nNOS/PSD-95 interaction in an in vit...
Eliprodil, a NR2B-NMDA receptor antagonist, was found to have neuroprotective activity in study of ischemia.
AM-36 is a potent blocker of batrachotoxinin (BTX)-sensitive Na+ channel binding in rat brain homogenates with an IC50 of 0.28 microM. As a unique neuroprotecti...
PEAQX(NVP-AAM 077) is a potent and orally active NMDA antagonist with a 15-fold preference for human NMDA receptors with the 1A/2A(IC50=270 nM), rather than 1A/...
Ro 25-6981 Maleate
The Maleate salt form of Ro 25-6981 which is a NMDA receptors blocker and has been found to exhibit neuroprotectant activity in vitro and in vivo. IC50: 9 nM.
Lanicemine, also know as AZD6765, has been to be a NMDA receptor antagonist that was once studiedd as a neuroprotective agent which was discontinued in 2007 and...
Amantadine is can be used as an antiviral and an antiparkinsonian drug. It is a NMDA receptor antagonist. Amantadine is also a useful building block in organic ...
LY-221501, a piperidine derivative, has been found to be a NMDA receptor antagonist.