|Description||Felbamate (Felbatol) is an anticonvulsant drug used in the treatment of epilepsy.|
GV-196771, an indole derivative, has been found to be a non-opioid analgesic agent which is also a NMDA antagonist binds to glycine-binding site and was once st...
CGP 43487 has been found to be a NMDA receptor antagonist and was once studied about its influenment of dopaminergic function as a supplement in the treatment o...
5,7-Dichlorokynurenic acid sodium salt
The sodium salt form of 5,7-Dichlorokynurenic acid, which is an effective antagonist at the glycine site of the NMDA receptor.
CP 101606 is a potent and selective NR2B antagonist of N-Methyl-D-Aspartate (NMDA) glutamate receptors. It decreases pentylenetetrazol-induced seizures.
Apimostinel is a selective partial agonist of an allosteric site of the glycine site of the NMDA receptor complex under investigation by Naurex. Its mechanism o...
Cgp 39551 is a selective and competitive N-methyl-D-aspartate (NMDA) receptor antagonist originated by Novartis. Ki is 310 nM for inhibition of [3H]-CPP binding...
Memantine is the first in a novel class of Alzheimer's disease medications acting on the glutamatergic system by blocking NMDA receptors.It is also a CYP2B6 and...
(R)-3-Carboxy-4-hydroxyphenylglycine has been found to be an antagonist of NMDA and AMPA/kainate receptor.
L-701,324 is a selective antagonist at the glycine site of the NMDA glutamate receptor. L-701,324 shows a beneficial action in the animal model of parkinsonian ...
D-Glutamic acid is a non-essential amino acid acting at NMDA receptors. D-Glutamic is less active than the L-isomer.
Homoquinolinic acid is a potent NMDA receptor agonist and neurotoxic agent.
Cgp 39653 is a competitive N-Methyl-D-aspartate (NMDA) receptor antagonist. CGP 39653 can selectively bins to the NMDA receptor as an antagonist with high affin...
CP-283097 is NR2B N-Methyl-D-Aspartate receptor antagonist originated by Pfizer. Preclinical trials for the treatment of Migraine and Neurodegenerative disorder...
7-Chlorokynurenic acid is a water-soluble and very potent NMDA receptor antagonist acting at the strychnine-insensitive glycine binding site. It is also a poten...
Trofinetide is a NMDA antagonist under the development of Neuren Pharmaceuticals. It is an analogue of the neuropeptide (1-3) IGF-1, which is a simple tripeptid...
TCN 201 is an NMDA receptor antagonist with selectivity for NR1/NR2A over NR1/NR2B-containing receptors (pIC50 = 6.8 and <4.3, respectively, in human recombinan...
Ifenprodil is an NMDA receptor antagonist and acts at the polyamine site. It is also an α2 adrenergic receptor ligand. It is selective for σ2 ligand over σ1 sit...
CGP 37849 is a potent, selective and competitive NMDA receptor antagonist (Ki = 35 nM). CGP 37849 exhibits an anticonvulsant effect following oral administratio...
D-CPP-ene has been found to be an effective and competitive NMDA antagonist.
Arcaine sulfate is the sulfate salt of arcaine, which is a potent, competitive and novel antagonist of the polyamine site on the NMDA receptor.