Fandosentan potassium - CAS 221246-12-4
Catalog number: 221246-12-4
Category: Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C25H17F3NO6S. K
Molecular Weight:
Endothelin Receptor
Fandosentan potassium is an endothelin A antagonist developed for the treatment of pulmonary hypertension.
Publictions citing BOC Sciences Products
  • >> More
White to off-white crystalline powder
potassium;4-(7-ethyl-1,3-benzodioxol-5-yl)-1,1-dioxo-2-[2-(trifluoromethyl)phenyl]-1$l^{6},2-benzothiazine-3-carboxylate; CI-1034; CI1034; PD 180988; PD180988
Boiling Point:
387.9ºC at 760 mmHg
Melting Point:
1.39 g/cm3
Canonical SMILES:
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Endothelin Receptor Products

CAS 221246-12-4 Fandosentan potassium

Fandosentan potassium
(CAS: 221246-12-4)

Fandosentan potassium is an endothelin A antagonist developed for the treatment of pulmonary hypertension.

Macitentan n-butyl analogue
(CAS: 556797-16-1)

Macitentan n-butyl analogue is a derivative of Macitentan, which is an antagonist/blocker of endothelin receptors on blood vessels and smooth muscle.

CAS 153042-42-3 BMS 182874

BMS 182874
(CAS: 153042-42-3)

BMS 182874 is an endothelin receptor antagonist used as an antihypertensive agent.

(CAS: 153624-15-8)

BMS-187308, a sulfonamide derivative, has been found to be an endothelin-A (ETA) antagonist that was once studied about its activity against pressor effect in r...

CAS 116303-65-2 Sarafotoxin S6b

Sarafotoxin S6b
(CAS: 116303-65-2)

Sarafotoxin S6b is a non-selective endothelin receptor agonist with vasoconstrictor activity.

CAS 441798-33-0 Macitentan

(CAS: 441798-33-0)

Macitentan is an orally available dual endothelin receptor (ETR) antagonist with potential antihypertensive and antineoplastic activity.

CAS 210421-74-2 Sitaxentan sodium

Sitaxentan sodium
(CAS: 210421-74-2)

Sitaxentan sodium inhibits ET-1-induced stimulation of phosphoinositide turnover with a Ki of 0.69 nM and a pA2 of 8.0.

(CAS: 150725-87-4)

RO462005 is an endothelin receptor selective agonist.

T-0201 Sodium
(CAS: 188307-16-6)

The sodium salt form of T-0201 which has been found to be an Endothelin A receptor antagonist that could be used as as anti-ischaemic agent and was once studied...

CAS 177036-94-1 Ambrisentan

(CAS: 177036-94-1)

Ambrisentan, a highly selective antagonist of the endothelin-1 type A receptor with IC50 of 18 nM, is indicated for the treatment of pulmonary arterial hyperten...

CAS 180384-56-9 Clazosentan

(CAS: 180384-56-9)

Clazosentan, also called as AXV 034, Ro 61-1790 or VML 588, a novel endothelin A antagonist, improves cerebral blood flow and behavior after traumatic brain inj...

CAS 144602-02-8 IRL-1038

(CAS: 144602-02-8)

IRL-1038 is an ETB endothelin receptor antagonist. It inhibits ETB receptor-mediated contraction of tracheal smooth muscle and guinea-pig ileal without any sign...

CAS 147536-97-8 Bosentan

(CAS: 147536-97-8)

Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.

CAS 157212-55-0 Bosentan Hydrate

Bosentan Hydrate
(CAS: 157212-55-0)

Bosentan inhibits the presser response to big ET-1 both after i.v. and oral administration, with a long duration of action and no intrinsic agonist activity.

CAS 173937-91-2 Atrasentan

(CAS: 173937-91-2)

atrasentan hydrochloride is the orally available hydrochloride salt of pyrrolidine-3-carboxylic acid with potential antineoplastic activity. As a selective anta...

CAS 123562-20-9 Endothelin 2 (human)

Endothelin 2 (human)
(CAS: 123562-20-9)

Endothelin 2 is a ligand for the endothelin (ET) receptors and a potent vasoconstrictor mainly found in the kidney and intestine.

CAS 142375-60-8 FR 139317

FR 139317
(CAS: 142375-60-8)

FR 139317 is a selective Endothelin A receptor antagonist originated by Fujisawa. (Ki values are 1 nM and 7.3 μM at ETA and ETB subtypes respectively). No devel...

(CAS: 1103522-45-7)

N-Despropyl-macitentan, an active metabolite of Macitentan, is a dual ET receptor antagonist with longer half-life than Macitentan. It has been proved to be eff...

CAS 156161-89-6 BQ 788 sodium salt

BQ 788 sodium salt
(CAS: 156161-89-6)

BQ 788 sodium salt is a potent, selective ETB receptor antagonist (IC50 = 1.2 nM) without significant activity on ETA receptor (IC50= 1300 nM).

CAS 117399-93-6 Endothelin 3 (human, rat)

Endothelin 3 (human, rat)
(CAS: 117399-93-6)

Endothelin 3 is a ligand of the endothelin (ET) receptors and a potent vasoconstrictor. Endothelin 3 increases blood pressure in spontaneously hypertensive and ...

Chemical Structure

CAS 221246-12-4 Fandosentan potassium

Quick Inquiry

Verification code

Featured Items