|Description||Ezetimibe produces a significant reduction in total cholesterol, LDL cholesterol, and triglycerides as well as a small but significant increase in HDL cholesterol.|
Epothilone F, an active metabolite of Epothilone D, prevents cancer cells from dividing by interfering with tubulin.
RSL3, a glutathione peroxidase 4 inhibitor, has been found to show selective response to tumor cells with oncogenic RAS.
Tetrahydrocurcumin is being studied for the treatment of cancer and dementia. It has antioxidant and anti-inflammatory properties. Tetrahydrocurcumin has been s...
Dixanthogen is the dominant species of xanthate adsorption on pyrite used as an ectoparasiticide.
Anti-inflammatory agent. MAPK inhibitor. Inhibits p38, ERK and JNK phosphorylation. Inhibits NFκB activation. Shows antitussive, expectorant and anti-inflammato...
D-Melphalan is an isomer of melphalan. Melphalan is Alkylating agent and DNA synthesis inhibitor using for the treatment of Multiple myeloma.
Deoxyadenosine is a substrate of bacterial methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase and a product inhibitor produced by radical SAM enz...
Rhynchophylline and isorhynchophylline act as noncompetitive antagonists of the NMDA receptor and that this property may contribute to the neuroprotective and a...
Vadadustat is a potent Hypoxia-inducible factor-proline dioxygenase inhibitor, which leads to stabilization and increased levels of HIFα. It is used for the tre...
DPY-2103 is a useful intermediate for chemical synthesis of a number of biologically active drugs.
EBI-907, an isoquinolin derivative, has been found to be a B-RafV600E inhibitor and exhibit activities against some oncogenic kinases at some extent. The resear...
EPZ020411, with potent anticancer activity, is an orally bioactive, selective inhibitor of PRMT6/8/1 with over 100-fold selective for other histone methyltransf...
Presatovir is a viral fusion protein inhibitor originated by Gilead Sciences with EC50 value of 0.43 nM. GS-5806 can inhibit a broad range of respiratory syncyt...
Eflornithine hydrochloride is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine ...
Acroteben is a bio-active chemical but no detailed information has been published yet.
RO5263397 is a selective trace amine-associated receptor 1(TAAR1) agonist. TAAR1 is a drug discovery target for cocaine addiction. RO5263397 is efficacious in r...
Miglitol is an oral anti-diabetic drug.
AT-61 is a nonnucleoside analogue inhibitors of hepatitis B virus (HBV) replication.
4-Aminobenzoic Acid, also called as PABA, was used as sunscreening agent at the past due to its UV absorption and antifibrotic properties.
This molecular is a phosphodiesterase 10A PET tracer. Related studies show that PDE10A activity can be reliably quantified and simplified using a reference tiss...