|Description||Evoxine (haploperine) is a furoquinoline alkaloid with hypnotic and sedative effects. It is found naturally in a variety of Australian and African plants including Evodia xanthoxyloides and Teclea gerrardii..|
Known as a weak hypotensive, moderate M- and N-cholinolytic pyrrolizidine alkaloid, xtracted from Trachelanthus Korolkowia.
Monomethylauristatin F Hcl(MMAF Hcl) is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin; lower cytotoxic activity than...
Mebicyphat is shown to be a non-competitive GABA antagonist. Blocks GABA gated Cl- channels, and is shown to inhibit dihydropicrotoxin
A muscarinic receptors antagonist.
Phencarol is used in the biological studies of azoniabicyclooctanes as muscarinic acetylcholine receptor antagonists.
Camptothecin (CPT) is a potent DNA enzyme topoisomerase I (topo I) inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.
Seco-Duocarmycin DMG is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates.
Daunorubicin Hcl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.
β-Bungarotoxin is a form of bungarotoxin that is fairly common in Krait (Bungaros multicinctus) venoms. A pre-synaptic toxin with enzymatic activity.
Syntheticquinazolone alkaloid, inhibiting cholinesterase activity in vitro.
Estrogenic activity; half agonist of estradiol receptors. Complex esters of phenolcarbon acids, , from plants of the Ferula genus, Umbelliferae.
Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 2...
organophosphoric inhibitor, SA-152, on the fibrinogen-coagulating and TAME-esterase activity of bovine α-thrombin.
Carothane complex ester , from plants of the Umbelliferae family.
7-Epi 10-Desacetyl Paclitaxel
7-Epi 10-Desacetyl Paclitaxel is a derivative of Paclitaxel, which is a microtubule polymer stabilizer with IC50 of 0.1 pM in human endothelial cells.
A native alkaloid A tropane alkaloid Extracted from Convolvulus subhirsitus plant.
an antagonist of the nicotinic acetylcholine receptor at the neuromuscular junction. Erabutoxin B from Laticauda semifasciata (Sea Snake)
Napelline is a diterpenoid alkaloid from plants of the Aconitum,genus, a potent antiarrhythmic with weak hypotensive and N-cholinoblocking effects.
A proanthocyanidin from Polygonum coriaricum, an antihypoxic.
Synthetic.alkaloid, a neuronal nicotinic AChR antagonist. Ganglioblocker.