|Description||Etretinate is a second-generation retinoid to treat severe psoriasis. It has been replaced by acitretin, a safer metabolite of etretinate.|
|Synonyms||Tegison; Tigason; Ro 10-9359|
Ginsenoside Rf, extracted from the traditional Chinese herb ginseng, an anti-arthritic agent, attenuating collagen-induced arthritis in mice.
Corylin is a major bioactive compound isolated from Psoralea corylifolia L. It is antibiotic or anticancer compound.
This active molecular is a potent cephalosporin antibiotic with a catechol moiety on the 3-position side chain under the development of Shionogi. Cefiderocol ex...
Xenin, a 25-amino acid peptide initially isolated from human gastric mucosa, has 6 C-terminal amino acids in common with amphibian xenopsin. Xenin may stimulate...
SHP099 is a potent and small-molecule inhibitor that has selectivity for SHP2 over SHP1 (IC50 = 0.071 μM), which is orally bioavailable. In xenograft models, SH...
Anethole, a widespread plant extract, could be used in various areas like foods and drugs as a flavoring agent. It might also block neuronal excitability.
Halcinonide is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.
CHF 1255, a tetrahydronaphthalen derivative, has been found to be probably effective against heart failure.
Methimazole (also known as Tapazole or Thiamazole or MMI) is an antithyroid drug,and part of the thioamide group. Like its counterpart propylthiouracil, a major...
CDy9, a pyrrolodiazaborinine derivative, has been found to be a fluorescent probe and could be used to detect and isolate intact stem cells.
Olesoxime (TRO19622) is an experimental neuroprotective drug. It is the lead compound of Trophos' cholesterol-oxime compound family of mitochondrial pore modula...
Coptisine is an alkaloid extract from the herbs of Chelidonium majus L, has been found to reversibly inhibit Monoamine oxidase A in mice.
Terpin hydrate is a kind of plant extract, which exists in various plant essential oils such as laurel and rosemary oil. It could be used in the treatment of ac...
Icariin is a flavonol glycoside, a type of flavonoid. Icariin is a PDE5 inhibitor with IC50 of 0.432 μM, 167-fold more selective for PDE5 than PDE4.
Lubiprostone induces a robust secretory response in T84 monolayers. Lubiprostone induces a rise in cAMP levels that was sensitive to EP(4)-receptor blockage in ...
Cot inhibitor-2 is a COT/Tpl2 inhibitor.
This active molecular is a selective and potent NK(3) antagonist. It has a high affinity for recombinant human (pK(i) value 8.9) and native guinea pig (pK(i) va...
GnRH-I, a small 10 amino acid long peptide (decapeptide) from the hypothalamus, has previously been demonstrated and shown to be biologically active in the immu...
BMS-505130 is a selective serotonin transport inhibitor with Ki of 0.18 nM. Ki value for binding to the norepinephrine is 4.6 mM and for dopamine transporters i...
OTS-964, a thienoquinolin derivative, is a TOPK inhibitor and prabably be useful in studying anticancer agent as an analogue of OTS-514. It is still under precl...