|Description||Ethynodiol diacetate is one of the first synthetic progestogens used in contraceptive pills.Relative to other 19-nortestosterone derivatives, it has relatively little or no potency as an androgen and also unlike most progestins in general, has significant estrogenic effects.|
Megestrol Acetate is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HepG2.
JNJ-1250132, a new steroidal progestin antagonist, inhibits binding of the receptor to DNA in vitro. JNJ-1250132 induces a receptor conformation more similar to...
Medroxy Progesterone is an orally active progestogen used in hormone replacement therepy (HRT).
Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.
AG-205 is a novel Pgrmc1 (progesterone receptor membrane component 1) inhibitor, alters the spectroscopic properties of the Pgrmc1-heme complex.
Ethynodiol diacetate is one of the first synthetic progestogens used in contraceptive pills.Relative to other 19-nortestosterone derivatives, it has relatively ...
Gestodene is a progestogen hormonal contraceptive.Gestodene is androgenically neutral, meaning that contraceptive pills containing gestodene do not exhibit the ...
Asoprisnil is a selective progesterone receptor (PR) modulator developed for the treatment of progesterone sensitive myomata.
Org OD 02-0
Org OD 02-0 is a membrane progesterone receptor agonist. Org OD 02-0 mimics the protective effects of progestin hormones on serum starvation-induced cell death ...
Chlormadinone acetate, with antiandrogen and antiestrogenic activities it is a steroidal progestin used in combinations as an oral contraceptive.
Ulipristal Acetate is an orally bioactive and selective progesterone receptor modulator (SPRM) used for emergency contraception and uterine fibroid. It binds to...
Tanaproget is a novel nonsteroidal progesterone receptor agonist that is first in its class and has high affinity and selectivity for the progesterone receptor....
Vilaprisan is a selective oral progesterone receptor antagonist under the development of Bayer HealthCare Pharmaceuticals. BAY 1002670 showed a marked dose-depe...
Altrenogest is a progestogen structurally related to veterinary steroid trenbolone.
Progesterone, synthesized from cholesterol by the sequential action of desmolase in the mitochondria, plays an important role in brain function as a endogenous ...
Drospirenone is a synthetic hormone used in birth control pills and postmenopausal hormone replacement therapy pills.
Mifepristone is a progesterone receptor antagonist(IC50= 0.2 nM) and a glucocorticoid receptor antagonist(IC50= 2.6 nM). It is used as an abortifacient in the f...
Nestorone is a steroidal progestin of the 19-norprogesterone group which is used as a hormonal contraceptive in several South American countries. It is a potent...
Telapristone acetate, also known as CDB-4124, acts as an investigational selective progesterone receptor modulator (SPRM) tested for treatment of progesterone s...
Dydrogesterone is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.