|Description||Ethynodiol diacetate is one of the first synthetic progestogens used in contraceptive pills.Relative to other 19-nortestosterone derivatives, it has relatively little or no potency as an androgen and also unlike most progestins in general, has significant estrogenic effects.|
Mifepristone is a progesterone receptor antagonist(IC50= 0.2 nM) and a glucocorticoid receptor antagonist(IC50= 2.6 nM). It is used as an abortifacient in the f...
Vilaprisan is a selective oral progesterone receptor antagonist under the development of Bayer HealthCare Pharmaceuticals. BAY 1002670 showed a marked dose-depe...
Drospirenone is a synthetic hormone used in birth control pills and postmenopausal hormone replacement therapy pills.
Levonorgestrel is a synthetic progestogen used as an active ingredient in some hormonal contraceptives.
Medroxy Progesterone is an orally active progestogen used in hormone replacement therepy (HRT).
Telapristone acetate, also known as CDB-4124, acts as an investigational selective progesterone receptor modulator (SPRM) tested for treatment of progesterone s...
AG-205 is a novel Pgrmc1 (progesterone receptor membrane component 1) inhibitor, alters the spectroscopic properties of the Pgrmc1-heme complex.
Altrenogest is a progestogen structurally related to veterinary steroid trenbolone.
Medroxyprogesterone acetate is a progestin, a synthetic variant of the human hormone progesterone and a potent progesterone receptor agonist.
Progesterone, synthesized from cholesterol by the sequential action of desmolase in the mitochondria, plays an important role in brain function as a endogenous ...
Megestrol Acetate is a synthetic progesteronal agent with an IC50 of 260 μM for the inhibition of HepG2.
Ethynodiol diacetate is one of the first synthetic progestogens used in contraceptive pills.Relative to other 19-nortestosterone derivatives, it has relatively ...
Norethindrone, a synthetic progestin, is an oral contraceptive involved in the inhibition of cytosolic sulfotransferases (SULT).
JNJ-1250132, a new steroidal progestin antagonist, inhibits binding of the receptor to DNA in vitro. JNJ-1250132 induces a receptor conformation more similar to...
Dienogest(STS-557) is a specific progesterone receptor agonist with potent oral endometrial activity and is used in the treatment of endometriosis.
Desogestrel is a progestogen with low androgenic potency used in hormonal contraceptives..
CP-8668 is an orally active nonsteroidal progesterone receptor modulator with no significant affinity for human glucocorticoid receptor or human estrogen recept...
Chlormadinone acetate, with antiandrogen and antiestrogenic activities it is a steroidal progestin used in combinations as an oral contraceptive.
Dydrogesterone is an orally active progestogen which acts directly on the uterus, producing a complete secretory endometrium in an estrogen-primed uterus.
Telapristone, the active metabolite of telapristone acetate (also known as CDB-4124), is a selective progesterone antagonist developed for the long-term treatme...