Estramustine phosphate sodium - CAS 52205-73-9
Catalog number:
52205-73-9
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
COA:
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Targets:
Microtubule/Tubulin
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Purity:
>98%
Synonyms:
estramustine Phosphate, Emcyt, Estracyt, Leo-299; Ro 22-2296/000.
MSDS:
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1.Effective and Safe Administration of Low-Dose Estramustine Phosphate for Castration-Resistant Prostate Cancer.
Inoue T1, Ogura K2, Kawakita M3, Tsukino H4, Akamatsu S1, Yamasaki T1, Matsui Y1, Segawa T5, Sugino Y3, Kamoto T4, Kamba T1, Tanaka S6, Ogawa O7. Clin Genitourin Cancer. 2016 Feb;14(1):e9-e17. doi: 10.1016/j.clgc.2015.08.008. Epub 2015 Sep 2.
Despite the favorable toxicity profile at the standard dose of 560 mg daily, the tolerability and toxicology of estramustine phosphate (EMP) have been a cause for concern at administration. Moreover, we do not know whether a lower dose of 280 mg of EMP daily can be administered with some efficacy and fewer side effects. The results of our phase II study suggest that low-dose EMP is a safe treatment option with the same efficacy in patients with castration-resistant prostate cancer.
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CAS 52205-73-9 Estramustine phosphate sodium

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