|Description||Eslicarbazepine acetate, (BIA 2-093), is a promising antiepileptic drug structurally related to Carbamazepine and Oxcarbazepine.|
|Synonyms||(10S)-10-(Acetyloxy)-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide; (S)-(-)-10-Acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide; BIA 2-093; Sep 0002093;|
Bavachalcone inhibited osteoclast formation from precursor cells with the IC(50) of approximately 1.5 microg ml(-1). The activation of MEK, ERK, and Akt by rece...
TP 064 is a potent and selective PRMT4 inhibitor with >100-fold selectivity over other histone methyltransferases and non-epigenetic targets. TP 064 inhibits me...
Ginsenoside Re, extracted from the traditional Chinese herb ginseng, responsible for some of the pharmacological functions.
KT 5926, an organic heterooctacyclic compound, selectively inhibits nerve growth factor-dependent neurite elongation.
Resiniferonol 9,13,14-Orthophenylacetate, a 20-Deacylated derivative of resiniferatoxin and tinyatoxin, is a transient receptor potential vanilloid-1 (TRPV1) ag...
Dienestrol is a synthetic and non-steroidal estrogen, which structurally related to stilbestrol. It is an estrogen receptor agonist and a metabolite of Diethyls...
10-Hydroxycamptothecin inhibits the growth of BT-20 and MDA-231 cell with IC50 of 34.3 nM and 7.27 nM, respectively, more potently than camptothecin (CPT) with ...
Ro18-5362 is the less active prodrug of Ro 18-5364 which is an extremely potent and rapid inhibitor of the gastric mucosal (H+ + K+)-ATPase.
YE 120 is a GPR35 agonist (EC50 = 32 nM in DMR assays), and also displays partial agonist activity in a β-arrestin translocation assay (EC50 = 10.2 μM).
LP-935509 is a brain penetrant inhibitor of adapter protein-2 associated kinase 1 (AAK1; IC50 value 3.3 nM and 14 nM and 320 nM for the closely related BIKE and...
A 77636 hydrochloride
A 77636 hydrochloride is a potent and selective dopamine D1-like receptor agonist (pEC50 = 8.97 and < 5 for D1-like and D2-like receptors, respectively). A 7763...
Bindarit treatment inhibits the release of MCP-1 from IL-1 stimulated osteoblast cell line Saos-2.
JNJ7925476 HCl is a novel triple monoamine uptake inhibitor. It blocks the serotonin transporter (SERT), norepinephrine transporter (NET) and dopamine transport...
MZ 1, a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4), retains high affinity for BRD2, BRD3 and B...
GLPG 0974 is a potent FFA2 antagonist (IC50 = 9 nM) with selectivity for FFA2 over FFA3. It was shown that GLPG 0974 inhibited acetate-induced human neutrophil ...
BAY-u 9773 is a non-selective cysteinyl leukotriene receptor antagonist displaying equal affinity for both CysLT1 and CysLT2 receptors (pKB = 6.8 and 6.5, respe...
VSV-G Peptide, a 11 amino acid peptide derived from the Vesicular Stomatitis viral glycoprotein, is commonly engineered onto the N- or C- terminus of a protein ...
4-O-β-D-Glucosyl-5-O-methyllvisamminol is a natural product isolated from the roots of Saposhnikovia divaricata (Turcz.) Schischk. It is a novel epigenetic supp...
Avarofloxacin hydrochloride is an antibacterial drug agent.
4’-Aminobenzanilide, a significant intermediate, could be widely used in the formation of drugs, dyestuff and agrochemicals.