ER-000444793 - CAS 792957-74-5
Category: Inhibitor
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Molecular Formula:
C23H18N2O2
Molecular Weight:
354.4
COA:
Inquire
Targets:
Others
Description:
ER-000444793, a potent inhibitor of mitochondrial permeability transition pore (mPTP) opening, inhibits mPTP with an IC50 of 2.8 μM. R-000444793 neither affected cyclophilin D (CypD) enzymatic activity, nor displaced of CsA from CypD protein, suggesting a mechanism independent of CypD inhibition.
Synonyms:
N-(2-benzylphenyl)-2-oxo-1H-quinoline-4-carboxamide; ER-000444793; ER 000444793; ER000444793
Solubility:
DMSO: ≥ 100 mg/mL
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
636.2±55.0 ℃ at 760 Torr
Density:
1.274±0.06 g/cm3
InChIKey:
OIZPRRGJIHYZAY-UHFFFAOYSA-N
InChI:
1S/C23H18N2O2/c26-22-15-19(18-11-5-7-13-21(18)24-22)23(27)25-20-12-6-4-10-17(20)14-16-8-2-1-3-9-16/h1-13,15H,14H2,(H,24,26)(H,25,27)
Canonical SMILES:
C1=CC=C(C=C1)CC2=CC=CC=C2NC(=O)C3=CC(=O)NC4=CC=CC=C43
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CAS 792957-74-5 ER-000444793

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