Epelsiban - CAS 872599-83-2
Catalog number:
872599-83-2
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C30H38N4O4
Molecular Weight:
518.65
COA:
Inquire
Targets:
Others
Description:
Epelsiban is an oxytocin receptor antagonist under the developement of GlaxoSmithKline. It has high affinity for the oxytocin receptor (Ki = 0.13 nM) with >31,000-fold selectivity over the related vasopressin receptors. No development was reported about Phase II clinical tirals for the treatment of premature ejaculation.
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Purity:
98%
Appearance:
Powder
Synonyms:
GSK-557296; GSK-557,296-B;(3R,6R)-6-((S)-sec-butyl)-3-(2,3-dihydro-1H-inden-2-yl)-1-((R)-1-(2,6-dimethylpyridin-3-yl)-2-morpholino-2-oxoethyl)piperazine-2,5-dione;1159097-48-9(besylate)
Solubility:
Soluble in DMSO
Storage:
-20℃ Freezer
MSDS:
Inquire
Application:
premature ejaculation
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long tim
Quantity:
Milligrams-Grams
InChIKey:
UWHCWRQFNKUYCG-QUZACWSFSA-N
InChI:
InChI=1S/C30H38N4O4/c1-5-18(2)26-28(35)32-25(23-16-21-8-6-7-9-22(21)17-23)29(36)34(26)27(24-11-10-19(3)31-20(24)4)30(37)33-12-14-38-15-13-33/h6-11,18,23,25-27H,5,12-17H2,1-4H3,(H,32,35)/t18-,25+,26+,27+/m0/s1
Canonical SMILES:
CCC(C)C1C(=O)NC(C(=O)N1C(C2=C(N=C(C=C2)C)C)C(=O)N3CCOCC3)C4CC5=CC=CC=C5C4
Current Developer:
Originator GlaxoSmithKline
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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