Epacadostat - CAS 1204669-58-8
Catalog number:
B0084-465275
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C11H13BrFN7O4S
Molecular Weight:
438.23
COA:
Inquire
Targets:
IDO
Description:
Epacadostat, also known as INCB024360 or INCB24360, is a potent and selective IDO1 inhibitor with IC50 of 71.8 nM±17.5 nM, with potential immunomodulating and antineoplastic activities. It has been shown to promote T and natural killer-cell growth, to increase IFN-γ production, and to reduce conversion to regulatory T (Treg)-like cells in a coculture system of human allogeneic lymphocytes with either dendritic cells or tumor cells.
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-465275 100 mg $249 In stock
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Related CAS:
1204669-37-3; 914471-09-3 (INCB024360-analog)
Appearance:
White to off-white solid powder
Synonyms:
(Z)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-((2-(sulfamoylamino)ethyl)amino)-1,2,5-oxadiazole-3-carboximidamide; INCB024360; INCB 024360; INCB-024360; INCB24360; INCB-24360; INCB 24360; Epacadostat
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
700.9±70.0 °C at 760 Torr
Density:
2.01±0.1 g/cm3
InChIKey:
FBKMWOJEPMPVTQ-UHFFFAOYSA-N
InChI:
1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23)
Canonical SMILES:
O=S(NCCNC1=NON=C1/C(NC2=CC=C(F)C(Br)=C2)=N/O)(N)=O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

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