|Description||Enzastaurin HCL is the hydrochloride salt of enzastaurin, a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply and so tumor burden.|
|Synonyms||Enzastaurin HCl; Enzastaurin Hydrochloride; LY317615; LY-317615; D04014; LY 317615.|
|Current Developer||Eli Lilly Inc|
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Ro 31-8220 Mesylate
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Enzastaurin HCL is the hydrochloride salt of enzastaurin, a synthetic macrocyclic bisindolemaleimide with potential antineoplastic activity. Binding to the ATP-...
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