Entrectinib (RXDX-101) - CAS 1108743-60-7
Catalog number:
1108743-60-7
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C31H34F2N6O2
Molecular Weight:
560.64
COA:
Inquire
Targets:
ALK
Description:
Entrectinib (RXDX-101) is an orally bioavailable pan-TrkA/B/C, ROS1 and ALK inhibitor with IC50 ranging between 0.1 and 1.7 nM. Phase 2.
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Purity:
98%
Appearance:
Solid powder
Synonyms:
NMS-E628
Solubility:
DMSO,100mg/mL(178.36mM);Ethanol,100mg/mL(178.36mM);Water,<1mg/mL(<1mM)
Storage:
3 years -20℃powder;6 months-80℃in solvent
MSDS:
Inquire
Shelf Life:
2 years if stored properly
Canonical SMILES:
CN1CCN(C2=CC(NC3CCOCC3)=C(C(/N=C4C5=C(NN/4)C=CC(CC6=CC(F)=CC(F)=C6)=C5)=O)C=C2)CC1
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