Endomorphin 1 - CAS 189388-22-5
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C34H38N6O5
Molecular Weight:
610.7
COA:
Inquire
Targets:
Opioid Receptor
Description:
Endomorphin 1 is a high affinity (Ki = 360 pM) and highly selective agonist of theμ-opioid receptor with 4000- and 15000-fold preference over δ and κ respectively and displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.
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Brife Description:
A high affinity, highly selective agonist of the μ-opioid receptor
Synonyms:
H-Tyr-Pro-Trp-Phe-NH2; L-tyrosyl-L-prolyl-L-tryptophyl-L-phenylalaninamide; (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Solubility:
DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
Boiling Point:
1052.8±65.0 ℃ at 760 Torr
Melting Point:
144-146 ℃
Density:
1.343±0.06 g/cm3
InChIKey:
ZEXLJFNSKAHNFH-SYKYGTKKSA-N
InChI:
1S/C34H38N6O5/c35-26(17-22-12-14-24(41)15-13-22)34(45)40-16-6-11-30(40)33(44)39-29(19-23-20-37-27-10-5-4-9-25(23)27)32(43)38-28(31(36)42)18-21-7-2-1-3-8-21/h1-5,7-10,12-15,20,26,28-30,37,41H,6,11,16-19,35H2,(H2,36,42)(H,38,43)(H,39,44)/t26-,28-,29-,30-/m0/s1
Canonical SMILES:
C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CC5=CC=CC=C5)C(=O)N
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CAS 189388-22-5 Endomorphin 1

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