Enasidenib mesylate - CAS 1650550-25-6
Category:
Inhibitor
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C20H21F6N7O4S
Molecular Weight:
569.48
COA:
Inquire
Targets:
Isocitrate Dehydrogenase (IDH)
Description:
Enasidenib mesylate is a first-in-class, oral, potent, reversible, selective inhibitor of the IDH2 mutant enzymes indicated for the treatment of adult patients with replased or refractory acute myeloid leukemia (AML) with an isocitrate dehydrogenase-2 (IDH2) mutation.
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Synonyms:
methanesulfonic acid;2-methyl-1-[[4-[6-(trifluoromethyl)pyridin-2-yl]-6-[[2-(trifluoromethyl)pyridin-4-yl]amino]-1,3,5-triazin-2-yl]amino]propan-2-ol; Enasidenib (mesylate); AG-221 mesylate; Enasidenib mesilate; Enasidenib methanesulfonate; Enasidenib mesylate [USAN]
Solubility:
DMSO
Storage:
Store in a cool and dry place (or refer to the Certificate of Analysis).
MSDS:
Inquire
InChIKey:
ORZHZQZYWXEDDL-UHFFFAOYSA-N
InChI:
1S/C19H17F6N7O.CH4O3S/c1-17(2,33)9-27-15-30-14(11-4-3-5-12(29-11)18(20,21)22)31-16(32-15)28-10-6-7-26-13(8-10)19(23,24)25;1-5(2,3)4/h3-8,33H,9H2,1-2H3,(H2,26,27,28,30,31,32);1H3,(H,2,3,4)
Canonical SMILES:
CC(C)(CNC1=NC(=NC(=N1)NC2=CC(=NC=C2)C(F)(F)F)C3=NC(=CC=C3)C(F)(F)F)O.CS(=O)(=O)O
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Chemical Structure

CAS 1650550-25-6 Enasidenib mesylate

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